Results 161 to 170 of about 1,451,652 (301)

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

AB₂X₄ spinel structures: similarity and differences between the centrosymmetric, Fd3m, and non-centrosymmetric, F4₁32, space groups. [PDF]

Acta Crystallogr B Struct Sci Cryst Eng Mater
Arakcheeva A, Magrez A, Chapuis G.
europepmc   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Cooperative Program In Space Science

, 2003
The mission of this activity, know as the Cooperative Program in Space Sciences (CPSS), is to conduct space science research and leading-edge instrumentation and technology development, enable research by the space sciences communities, and to expedite ...
Black, David
core  

Phylogenetic tree inference from single-cell RNA sequencing data with SCITE-RNA. [PDF]

Genome Biol
Zimmermann N, Sun X, Hård J, Kuipers J, Beerenwinkel N.   +4 more
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Lunar and Planetary Science at the National Space Science Data Center

The Lunar & Planetary Science section of the National Space Science Data Center (NSSDC) archives distributes "planetary and lunar data and images obtained from spacecraft missions (both NASA and non-NASA)." Users can find fact sheets ...

core  

Spatially distributed complex organic matter detected in an ancient river valley in Jezero crater, Mars. [PDF]

Sci Adv
Murphy AE, Uckert K, Hand KP, Bhartia R, Bykov SV, Hickman-Lewis K, Jakubek RS, Lee C, McCubbin FM, Minitti ME, Pascuzzo A, Siljeström S, Sharma S, Steele A, Williford KH, Abbey W, Asher SA, Barnes R, Barr PA, Bell JF, Beyssac O, Bosak T, Bramble MS, Brown A, Broz AP, Buckner D, Cardarelli EL, Carsten JL, Corpolongo A, Czaja A, Edgington SGC, Ehlmann BL, Farley KA, Fornaro T, Fries M, González-Burgos R, Gupta S, Haney NC, Hug W, Huggett J, Hurowitz JA, Imbeah S, Clark J, Jones AJ, Kah LC, Kennedy MR, Lee SW, Maki J, Nixon B, Núñez JI, Osterhout JT, Phelan ND, Phua YY, Ravine MA, Hollis JR, Scheller E, Schulte MD, Sephton MA, Simon JI, Srivastava A, Stack KM, Van Beek J, Weiss BP, Wiens R, Williams AJ, Wogsland BV, Yingst RA.   +66 more
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source