Results 31 to 40 of about 39,519 (258)

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Evaluating U-Space for UAM in Dense Controlled Airspace

Drones, 2023
The operation of unmanned aircraft systems in shared airspace can serve as an accelerator for the global economy and a sensitive addition to the existing mix of transportation modes.
Michal Černý, Adam Kleczatský, Tomáš Tlučhoř, Milan Lánský, Jakub Kraus   +4 more
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Diabetes‐Associated Cognitive Impairment: Pathophysiology and Emerging Therapies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Diabetes‐associated cognitive impairment (DACI) is a common yet underrecognized condition, manifesting along a spectrum from mild cognitive impairment to dementia. DACI encompasses patients who develop vascular dementia (VaD) or Alzheimer's disease (AD) with diabetes as a risk factor; however, in certain patients, particularly those lacking ...
Osman Corbali, Priyanka Menon, Halil I. Corbali, Ram Jagannathan, Allan I. Levey   +4 more
wiley   +1 more source

A Holistic Platform Approach for Developing Robust Pulmonary mRNA Delivery: Integrating Novel Phenolic Acid‐Derived Ionizable Lipids and Device Engineering

Advanced Functional Materials, EarlyView.
An integrated pulmonary mRNA delivery platform combining novel biodegradable syringic acid‐derived ionizable lipids, design‐of‐experiments formulation optimization, and vibrating‐mesh nebulizer engineering enabled stable aerosolization and efficient lung delivery.
Neha Kaushal, Younan Ma, Asad Khanmohammed, Dipen Parande, Hanming Zhang, Saket Dolare, Juliet Chen, Apiwat Wangweerawong, Saswata Karmakar, Hongfeng Deng, Frank Koppenhagen, Shraddha Sharma, Eric Reyes, Sherry He, Lianne Boeglin, Caroline Woo, Azadeh Paksa, Ayed Allawzi, Anusha Dias, Gregory Troiano, Shrirang Karve, Frank DeRosa   +21 more
wiley   +1 more source

Trans‐Space: Space Computing Based Spatiotemporal Resources Optimization for Signalized Intersection with Transfer Learning

IET Intelligent Transport Systems
The optimization of spatial and temporal resources at signalized intersections is a critical aspect of intelligent transportation systems. Traditional traffic signal control methods, which usually rely on fixed signal timings and lane assignments, are ...
Xin Qu, Qingyuan Ji, Wei Tan, Shumin Yu, Chao Li, Daoxun Li   +5 more
doaj   +1 more source

Space traffic management in the new space era

Journal of Space Safety Engineering, 2019
Abstract Major changes are expected in the space environment due to the imminent launch of NewSpace (sometimes Space 2.0) systems, particularly large low Earth orbit (LEO) constellations that will change the space operations environment. This new activity could overwhelm current space flight safety processes. However, there are many encouraging signs
Theodore J. Muelhaupt, Marlon E. Sorge, Jamie Morin, Robert S. Wilson   +3 more
openaire   +1 more source

System Autonomy for Space Traffic Management [PDF]

2018 IEEE/AIAA 37th Digital Avionics Systems Conference (DASC), 2018
This paper proposes an initial architecture for a Space Traffic Management (STM) system, based on openApplication Programming Interfaces (APIs) and drawing on previous work by the NASA Ames Research Center (ARC) to develop an architecture for low-altitude Unmanned Aerial System Traffic Management (UTM). The authors explore how autonomy could be used to
Sreeja Nag, David Murakami, Miles Lifson, Parimal Kopardekar   +3 more
openaire   +1 more source

Hemocompatible Glycogen‐Tissue Plasminogen Activator Complexes for Enhanced Blood Clot Dissolution

Advanced Healthcare Materials, EarlyView.
Glycogen–heparin‐cRGD nanoparticles enable targeted delivery of tissue plasminogen activator (tPA) to thrombi through activated platelet recognition. The hemocompatible hybrids minimize interactions with blood and immune cells while retaining enzymatic biodegradability.
Nadiia Davydiuk, Vaidehi Londhe, Susanne Boye, Martin Müller, Carsten Werner, Manfred F. Maitz, Quinn A. Besford   +6 more
wiley   +1 more source

Real-Time Traffic State Measurement Using Autonomous Vehicles Open Data

IEEE Open Journal of Intelligent Transportation Systems, 2023
Autonomous vehicle (AV) technologies are expected to disrupt the existing urban transportation systems. AVs’ multi-sensor system can generate large amount of data, often used for localization and safety purposes.
Zhaohan Wang, Profita Keo, Meead Saberi
doaj   +1 more source