Results 101 to 110 of about 19,402,803 (295)
, 2013 A fundamental difference between signed and spoken languages is that in signed languages the signer uses the three dimensional space in front of him/her (signing space) and his/her own body for reference and cohesion.
Nilsson, Anna-Lena,
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Surveying the Creative Use of Vacant Space in London, c.1945-95 [PDF]
, 2019 This paper draws on a Leverhulme-funded research project entitled ‘Interim spaces and creative use’ (2012-2014). The project investigated five present-day temporary projects sited on vacant land in London.
Kamvasinou, K., Milne, S.
core +1 more source
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
FEBS Letters, EarlyView.Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
Ecology and EvolutionWithin mixed‐species assemblages, closely related species may face interspecific competition and reproductive interference. Species may evolve adaptations to outcompete or coexist, though most assemblages likely exist in a nonequilibrium state between ...
Jenny Y. Sung +2 more
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Micro-Climate and the Use of Kampong-Kota Communal Space
, 2020 Communal outdoor space functions as a social space, especially in dense urban housing, such as in a city. The microclimate represents local climatic conditions consisting of temperature, humidity, wind and solar radiation.
Inavonna, Inavonna +2 more
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FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Western spotted skunk spatial ecology in the temperate rainforests of the Pacific Northwest
EcosphereA major threat to small mammalian carnivore populations is human‐induced land use change, but conservation and management are inhibited by limited knowledge about their ecology and natural history. To fill a key knowledge gap of the western spotted skunk
Marie I. Tosa +2 more
doaj +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source