Results 51 to 60 of about 2,159,529 (317)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Mapping potential landfill sites for North Sinai cities using spatial multicriteria evaluation

open access: yesEgyptian Journal of Remote Sensing and Space Sciences, 2012
The exponential rise in the urban population of the developing countries during the past decades accelerated the urbanization phenomenon and the great need for solid waste management.
Hala A. Effat, Mohamed N. Hegazy
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Enhancing land suitability assessment through integration of AHP and GIS-based for efficient agricultural planning in arid regions

open access: yesScientific Reports
Land Suitability Assessment (LSA) aids in identifying optimal crop cultivation sites; thereby, it is the key factor for proper planning to maximize production yield.
Mohamed A. E. AbdelRahman   +2 more
doaj   +1 more source

How Eurasian otters (Lutra lutra) use suboptimal habitats? Space use dynamics in forest streams of Central Russian Upland

open access: yesNature Conservation Research: Заповедная наука, 2022
Territoriality is the regulating social system for many carnivore species. It is usually determined by resource abundance and competition. Lutra lutra (hereinafter also – Eurasian otter), a top freshwater predator, has a wide range of various types of ...
Nadezhda A. Sokolova   +3 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Fine‐scale movements and behaviors of coyotes (Canis latrans) during their reproductive period

open access: yesEcology and Evolution, 2021
In canids, resident breeders hold territories but require different resources than transient individuals (i.e., dispersers), which may result in differential use of space, land cover, and food by residents and transients.
Michael J. Chamberlain   +4 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Waterfowl recently infected with low pathogenic avian influenza exhibit reduced local movement and delayed migration

open access: yesEcosphere, 2023
Understanding relationships between infection and wildlife movement patterns is important for predicting pathogen spread, especially for multispecies pathogens and those that can spread to humans and domestic animals, such as avian influenza viruses ...
Claire S. Teitelbaum   +10 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

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