Results 71 to 80 of about 2,450,404 (270)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

A Novel SVPWM Algorithm for 3-phase 3-level Converter

Kongzhi Yu Xinxi Jishu, 2011
As for the three-phase three-level voltage source converter, a simple SVPWM algorithm based on the sector mapping for controlling three-level converter is proposed. Correctness of the algorithm is verified by the simulation results.
LI Jianghong, HU Zhaowen, CHEN Huaguo, XU Wei   +3 more
doaj  

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

Direct Power Control Strategy based on Space Vector Modulation

Kongzhi Yu Xinxi Jishu, 2010
Direct power control technology is applied on three-phase PWM rectifier. Using space vector modulation instead of switching tables can eliminate the bad effect of unconstant switching frequency on the rectifier.
张明莲, 吕瑞强, 王慧
doaj  

On the Shintani zeta function for the space of binary tri-Hermitian forms

, 1995
In this paper, we consider the most non-split parabolic D_4 type prehomogeneous vector space. The vector space is an analogue of the space of Hermitian forms.
Yukie, Akihiko
core   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

Parallelogram Based Method for Space Vector Pulse Width Modulation

Revista Facultad de Ingeniería Universidad de Antioquia, 2013
This paper presents a parallelogram based duty cycle computation method for space vector modulation control using standard pulse width modulation circuitry.
José Restrepo, Víctor Guzmán, María Giménez, Alexander Bueno, José Aller   +4 more
doaj  

Space Vector Design Assisted Channel Modulation

IEEE Access
With the design idea of the index modulation (IM), media-based modulation (MBM) has been attracted a lot of attention due to that it not only offers optional transmission channels for physical security but also transmits additional channel index (CI ...
Shuqing Lin, Yanfei Zhu, Zhi Yang
doaj   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source