Results 41 to 50 of about 557,453 (348)

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Hybrid Space Vector PWM Strategy for Three-Phase VIENNA Rectifiers

open access: yesSensors, 2022
Vienna rectifiers are widely used, but they have problems of zero-crossing current distortion and midpoint potential imbalance. In this paper, an improved hybrid modulation strategy is proposed.
Yaodong Wang   +3 more
doaj   +1 more source

Multilevel Multiphase Feedforward Space-Vector Modulation Technique [PDF]

open access: yes, 2010
Multiphase converters have been applied to an increasing number of industrial applications in recent years. On the other hand, multilevel converters have become a mature technology mainly in medium- and high-power applications.
Doval Gandoy, Jesús   +6 more
core  

Bending and Breaking of Stripes in a Charge-Ordered Manganite [PDF]

open access: yes, 2017
In complex electronic materials, coupling between electrons and the atomic lattice gives rise to remarkable phenomena, including colossal magnetoresistance and metal-insulator transitions.
Admasu, Alemayehu S.   +6 more
core   +3 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

MODELING OF DYNAMIC SYSTEMS WITH MODULATION BY MEANS OF KRONECKER VECTOR-MATRIX REPRESENTATION [PDF]

open access: yesНаучно-технический вестник информационных технологий, механики и оптики, 2015
The paper deals with modeling of dynamic systems with modulation by the possibilities of state-space method. This method, being the basis of modern control theory, is based on the possibilities of vector-matrix formalism of linear algebra and helps to ...
A. S. Vasilyev, A. V. Ushakov
doaj   +1 more source

A Modified Neutral Point Balancing Space Vector Modulation for Three-Level Neutral Point Clamped Converters in High-Speed Drives

open access: yesIEEE transactions on industrial electronics (1982. Print), 2019
This paper describes a high-performance neutral point voltage balancing technique for a neutral point clamped (NPC) converter. Conventional neutral point voltage balancing methods do not function well under low power factor, low pulse ratio, and near ...
Chen Li   +6 more
semanticscholar   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Discontinuous PWM strategy considering neutral-point potential balance for a three-level NPC inverter

open access: yes工程科学学报, 2016
A novel discontinuous space-vector pulse width modulation(DSVPWM) strategy is proposed for a three-level neutralpoint-clamped(NPC) voltage source inverter.
LUO Xiao-fei   +3 more
doaj   +1 more source

Indirect 3D-Space Vector Modulation for Matrix Converter [PDF]

open access: yesEngineering, Technology & Applied Science Research, 2018
This paper discusses the indirect space vector modulation for four-leg matrix converter. Four-leg matrix converter has been proven to be a reliable, cost-effective, and compact power electronic interface to supply unbalanced or nonlinear loads. However, the added fourth leg has shifted the inverter side modulation from simple two-dimension SVM into ...
Abdelrehim, Ahmed   +3 more
openaire   +1 more source

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