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Pharmacodynamic Aspects of Spaceflight
The Journal of Clinical Pharmacology, 1991Little is known at present about the effects of human exposure to microgravity on the pharmacodynamics of medicinal agents. Considering the known physiologic perturbations associated with spaceflight and the effects of some of these perturbations on the pharmacodynamics of certain medicinals that act on the central nervous system, it is likely that the
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Spaceflight causes mitochondrial stress
Nature Reviews Genetics, 2020An article in Cell describes a multi-omic analysis of health risks from spaceflights that implicates mitochondrial stress and dysregulation as key drivers.
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Orientation Illusions in Spaceflight
Journal of Vestibular Research, 1997Investigations of spontaneous illusory reactions were carried out during spaceflights of various durations by ANKETA questionnaires (104 cosmonauts). From a total of 104 cosmonauts, 24, in addition, used a dictaphone to record a verbal description of the illusions and their sensations on tape.
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