Adjuvant pharmacological strategies for the musculoskeletal system during long‐term space missions
British Journal of Clinical Pharmacology, EarlyView., 2023 Abstract Despite 2 h of daily exercise training, muscle wasting and bone loss are still present after 6‐month missions to the international space station. Some crew members lose bone much faster than others. In preparation for missions to the Moon and Mars, space agencies are therefore reviewing their countermeasure portfolios.
Friederike Thomasius +2 more
wiley +1 more source
Alterations in Saliva and Plasma Cytokine Concentrations During Long-Duration Spaceflight
Frontiers in Immunology, 2021 Long-duration spaceflight is known to cause immune dysregulation in astronauts. Biomarkers of immune system function are needed to determine both the need for and effectiveness of potential immune countermeasures for astronauts.
Stephanie S. Krieger +9 more
doaj +1 more source
An Observation‐Driven Approach to Improve Vegetation Phenology in a Global Land Surface Model
Journal of Advances in Modeling Earth Systems, 2020 An empirical model calibration approach is presented that aims to approximate missing biosphere processes in a global land surface model without the need for substantial model structural changes.
Jana Kolassa +5 more
doaj +1 more source
Genetic dissection of the Arabidopsis spaceflight transcriptome: Are some responses dispensable for the physiological adaptation of plants to spaceflight? [PDF]
PLoS ONE, 2017 Experimentation on the International Space Station has reached the stage where repeated and nuanced transcriptome studies are beginning to illuminate the structural and metabolic differences between plants grown in space compared to plants on the Earth ...
Anna-Lisa Paul +5 more
doaj +1 more source
Cardiovascular deconditioning during long-term spaceflight through multiscale modeling [PDF]
npj Microgravity 6(1), 27, 2020, 2020 Human spaceflight has been fascinating man for centuries, representing the intangible need to explore the unknown, challenge new frontiers, advance technology and push scientific boundaries further. A key area of importance is cardiovascular deconditioning, that is, the collection of hemodynamic changes - from blood volume shift and reduction to ...
arxiv +1 more source
Root Skewing-Associated Genes Impact the Spaceflight Response of Arabidopsis thaliana
Frontiers in Plant Science, 2020 The observation that plant roots skew in microgravity recently refuted the long-held conviction that skewing was a gravity-dependent phenomenon. Further, spaceflight root skewing suggests that specific root morphologies and cell wall remodeling systems ...
Brandon Califar +13 more
doaj +1 more source
Scientific Reports, 2022 Long-duration spaceflight impacts human physiology, including well documented immune system dysregulation. The space food system has the potential to serve as a countermeasure to maladaptive physiological changes during spaceflight.
Grace L. Douglas +15 more
doaj +1 more source
Neurosurgery and Manned Spaceflight [PDF]
Neurosurgery, 2018 ABSTRACT There has been a renewed interest in manned spaceflight due to endeavors by private and government agencies. Publicized goals include manned trips to or colonization of Mars. These missions will likely be of long duration, exceeding existing records for human exposure to extra-terrestrial conditions.
Sandip S. Panesar +3 more
openaire +3 more sources
In situ synthesis of high dielectric constant GNPs/PBO nanocomposites with enhanced thermostability
IET Nanodielectrics, 2019 Graphite nanoparticles (GNPs) were introduced into poly(p-phenylene benzobisoxazole) (PBO) matrix to produce composites via in situ polymerisation. Films of various composites were fabricated through the solution casting method in methanesulfonic acid ...
Yi Chen +6 more
doaj +1 more source
A Material-based Panspermia Hypothesis: The Potential of Polymer Gels and Membraneless Droplets [PDF]
Biopolymers, 113, 5, e23486, 2022, 2022 The Panspermia hypothesis posits that either life's building blocks (molecular Panspermia) or life itself (organism-based Panspermia) may have been interplanetary transferred to facilitate the Origins of Life (OoL) on a given planet, complementing several current OoL frameworks.
arxiv +1 more source