Results 81 to 90 of about 19,941 (243)
Putting the brakes on muscle growth: Myostatin as regulator of disuse atrophy
Experimental Physiology, EarlyView.Abstract Skeletal muscle is a highly plastic tissue that rapidly adapts to changes in mechanical loading and metabolic activity. Periods of inactivity, including bed rest, limb immobilization or microgravity, induce a pronounced loss of muscle mass and function.
Derk H. C. Nieuwenhuijsen +2 more
wiley +1 more source
THE SPACEFLIGHT ENVIRONMENT AND THE SKELETAL SYSTEM [PDF]
, 2008 The spaceflight environment presents many challenges to the human body. Bone loss in astronauts is a well known consequence of reduced loading in the weightless environment of low-earth orbit.
Bandstra, Eric
core +1 more source
Spaceflight alters host-gut microbiota interactions [PDF]
The ISS rodent habitat has provided crucial insights into the impact of spaceflight on mammals, inducing symptoms characteristic of liver disease, insulin resistance, osteopenia, and myopathy.
Tierney, Braden T. +8 more
core +1 more source
Experimental Physiology, EarlyView.Abstract Bed rest accelerates bone loss and may exacerbate skeletal fragility. This study examined the effects of 14 days of head‐down tilt bed rest (HDBR) with or without exercise, and subsequent recovery, on bone turnover, density and structure in older adults. Twenty‐two healthy older adults (55–65 years) completed the HDBR protocol.
Guy Hajj‐Boutros +11 more
wiley +1 more source
Cooling down for going up: Could selective ‘brain chilling’ mitigate high‐altitude illness?
Experimental Physiology, EarlyView.
Adnan Haq, Damian M. Bailey
wiley +1 more source
Experimental Physiology, EarlyView.Abstract Long‐term space travel (e.g. travel to Mars) will greatly exceed the recommended lifetime radiation dose of 600 millisieverts (mSv) and have a detrimental effect on skeletal fragility. Our objective was to determine if 1 Gray (GY) radiation impacts the biomechanical properties of the tibia and femur from rats under microgravity.
Brent J. F. Hill, Rahul Mehta
wiley +1 more source
The Trends in Global Gene Expression in Mouse Embryonic Stem Cells During Spaceflight
Frontiers in Genetics, 2019 The environment in space differs greatly from the environment on the ground. Spaceflight causes a number of physiological changes in astronauts, such as bone loss and immune system dysregulation.
Lili An +18 more
doaj +1 more source
Water and wisdom: Hydration as a defence against dementia
Experimental Physiology, EarlyView.
David C. Byfield, Damian M. Bailey
wiley +1 more source
Exercise intolerance and impaired aerobic capacity in heart transplant recipients
Experimental Physiology, EarlyView.Abstract Heart transplant recipients exhibit reduced exercise tolerance and persistently diminished aerobic capacity despite exercise training. Exercise tolerance depends on integrated oxygen transport and utilization, which are impaired in heart transplant recipients.
Fred W. Kolkhorst +2 more
wiley +1 more source
McGill Journal of Medicine, 2020 Introduction: Spaceflight alters normal physiology of cells and tissues seen on Earth. Immune cells and signaling molecules appear to be particularly affected, resulting in changes in leukocyte populations, killing ability and effector function, and ...
Adil S. Ahmed +3 more
doaj