Results 51 to 60 of about 5,467,910 (302)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Hydrogel spacer distribution within the perirectal space in patients undergoing radiotherapy for prostate cancer: Impact of spacer symmetry on rectal dose reduction and the clinical consequences of hydrogel infiltration into the rectal wall.

open access: yesPractical Radiation Oncology, 2017
PURPOSE Hydrogel prostate-rectum spacers, biomaterials placed between the prostate and rectum, continue to gain interest as a method to reduce or limit rectal dose during dose escalated prostate cancer radiation therapy.
B. Fischer-Valuck   +4 more
semanticscholar   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Bow-Tie Microwave Diodes on the Base of Modulation-Doped Semiconductor Structure with Wide Spacer: Theory and Experiment

open access: yesCrystals
Bow-tie microwave diodes have proven to be effective sensors of electromagnetic radiation across a wide wavelength range, from centimeter-scale radio waves to micrometer-scale mid-infrared radiation. Their operation is based on electron heating by strong
Algirdas Sužiedėlis   +5 more
doaj   +1 more source

The effect of feed spacer geometry on membrane performance and concentration polarisation based on 3D CFD simulations

open access: yes, 2017
Feed spacers are used in spiral wound reverse osmosis (RO) membrane modules to keep the membrane sheets apart as well as to enhance mixing. They are beneficial to membrane performance but at the expense of additional pressure loss.
Boram Gu, C. Adjiman, Xiao-Yan Xu
semanticscholar   +1 more source

Molecular recordings by directed CRISPR spacer acquisition

open access: yesScience, 2016
INTRODUCTION Although recent advances in DNA synthesis and sequencing technologies have made practical the writing and readout of arbitrary data in the form of synthetic DNA, still lacking are the robust tools necessary to generate a dynamic record of ...
Seth L. Shipman   +3 more
semanticscholar   +1 more source

Direct and Energy-Transfer-Mediated Charge-Transfer State Formation and Recombination in Triangulene-Spacer-Perylenediimide Multichromophores: Lessons for Photovoltaic Applications

open access: yes, 2019
We study the dynamics of primary photoexcitations in three symmetric donor–spacer–acceptor–spacer–donor multichromophores with increasing oligophenylene spacer length, following selective donor or acceptor excitation.
Julien Gorenflot (1278303)   +6 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Antibiotic Elution from Cement Spacers and Its Influencing Factors

open access: yesAntibiotics
Antibiotic-loaded cement spacers play a crucial role in two-stage revision arthroplasty of infected total hip and knee prostheses. There is still controversy regarding whether the elution from antibiotic-loaded cement spacers is greater than the MIC for ...
Bernd Fink, Kevin D. Tetsworth
doaj   +1 more source

A case of treatment of a fungal periprosthetic infection with a carbon-coated implant

open access: yesВестник медицинского института «Реавиз»: Реабилитация, врач и здоровье, 2023
Background. Arthroplasty is the most common surgical treatment for patients with end-stage knee arthrosis. From 2 to 7% of those operated on are patients with rheumatoid arthritis. The inflammatory process in the joint, low rehabilitation potential, long-
L. I. Malyuchenko   +4 more
doaj   +1 more source

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