Results 81 to 90 of about 5,467,910 (302)
JSES International, 2020 Background: The treatment of septic arthritis, caused by either hematogenous seeding, injections, or surgery, can be challenging. Staged reverse shoulder arthroplasty (RSA) with temporary implantation of an antibiotic-loaded spacer is widely accepted but
Sebastian Philipp Boelch, MD +5 more
doaj +1 more source
Enhancement of the superconducting transition temperature of FeSe by intercalation of a molecular spacer layer. [PDF]
Nature Materials, 2012 The discovery of high-temperature superconductivity in a layered iron arsenide has led to an intensive search to optimize the superconducting properties of iron-based superconductors by changing the chemical composition of the spacer layer between ...
Matthew Burrard-Lucas +10 more
semanticscholar +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Spacer-Programmed Two-Dimensional DNA Origami Assembly
Two-dimensional (2D) DNA origami assembly represents a powerful approach to the programmable design and construction of advanced 2D materials. Within the context of hybridization-mediated 2D DNA origami assembly, DNA spacers play a pivotal role as ...
Sisi Jia (728468) +8 more
core +1 more source
Spacer-Assisted Amine-Coiled Carbon Nanotubes for CO2 Capture
, 2019 Architecture of a DNA-wrapped carbon nanotube (CNT) inspires rational design of a polymer-wrapped CNT effective for CO2 capture. Polyethyleneimine (PEI) selected as a spiral wrapper of CNT is modified by insertion of spacer molecules loaded with amino ...
Mengmeng Deng (3844747) +1 more
core +1 more source
, 2023 Significant downstream performance reduction and concentration polarisation reduce direct contact membrane distillation (DCMD) efficiency. These challenges are not well researched since they are difficult to implement experimentally and numerically ...
Thiel, David V +7 more
core +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Cas1–Cas2 complex formation mediates spacer acquisition during CRISPR–Cas adaptive immunity
Nature Structural &Molecular Biology, 2014 The initial stage of CRISPR–Cas immunity involves the integration of foreign DNA spacer segments into the host genomic CRISPR locus. The nucleases Cas1 and Cas2 are the only proteins conserved among all CRISPR–Cas systems, yet the molecular functions of ...
J. K. Nuñez +5 more
semanticscholar +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Cancer immunology research, 2014 Hudecek, Sommermeyer, and colleagues show that modifications of the length and composition of the extracellular spacer of a chimeric antigen receptor (CAR) that abrogate its binding to Fc receptors can prevent off-target activation of CAR T cells and ...
M. Hudecek +7 more
semanticscholar +1 more source