Results 101 to 110 of about 5,467,910 (302)

Towards spacer free electrodialysis [PDF]

, 2009
In electrodialysis (ED) processes, the operating current density is limited by concentration polarisation. However, in order to get the maximum ion flux per unit membrane area it is desirable to operate at the highest possible current density.
Stamatialis, Dimitrios, Balster, J.H., Balster, J., Stamatialis, D.F., Wessling, Matthias, Wessling, M.   +5 more
core   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

CFD EVALUATION OF EFFECTIVENESS OF THE THREE-LAYER SPACERS FOR THE SPIRAL WOUND MEMBRANE MODULES

Ecology, Human, Society
In the current work the evaluation of the effectiveness of the new design of spacer for the spiral wound membrane modules using computational fluid dynamics methods of the computational fluid dynamics is represented.
Serhii HULIIENKO
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

How Does Inter-Epitope Spacer Variation Within Artificial Immunogens Based on T-Cell Epitopes of Tick-Borne Encephalitis Virus Affect Immunogenicity?

Vaccines
Background/Objectives: In recent years, researchers have directed considerable attention toward the activation of the T-cell response in the development of vaccines against viral infections, including the tick-borne encephalitis virus (TBEV).
Elena V. Yakovleva, Denis V. Antonets, Mariya B. Borgoyakova, Ekaterina V. Starostina, Vladimir A. Yakovlev, Elizaveta V. Shaburova, Denis N. Kisakov, Lyubov A. Kisakova, Olga Y. Volkova, Nadezhda B. Rudometova, Andrey P. Rudometov, Larisa I. Karpenko   +11 more
doaj   +1 more source

Experimental Investigation of Thermal Behaviors in Window Systems by Monitoring of Surface Condensation Using Full-Scale Measurements and Simulation Tools

Energies, 2016
The aim of the present study was to investigate the thermal performance of window systems using full-scale measurements and simulation tools. A chamber was installed on the balcony of an apartment to control the temperatures which can create condensation
Goopyo Hong, Daeung Danny Kim, Byungseon Sean Kim   +2 more
doaj   +1 more source

Presentation_1_Finite Element-Based Personalized Simulation of Duodenal Hydrogel Spacer: Spacer Location Dependent Duodenal Sparing and a Decision Support System for Spacer-Enabled Pancreatic Cancer Radiation Therapy.pptx

, 2022
PurposePancreatic cancer is the fourth leading cause of cancer-related death, with a very low 5-year overall survival rate (OS). Radiation therapy (RT) together with dose escalation significantly increases the OS at 2 and 3 years.
Todd McNutt (7055747), Eun Ji Shin (597018), Avani Dholakia Rao (12282524), Junghoon Lee (640941), John Wong (323086), Chen Hu (317374), Amol Narang (12282521), Sina Youssefian (5851334), Sarah Han-Oh (10333206), Kai Ding (783198), Hamed Hooshangnejad (12282518)   +10 more
core   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Molecular markers, analysis and the population genetics of parasites [PDF]

, 2002
In this study different molecular techniques are contrasted (RAPD's, allozyme, sequencing mtDNA, sequencing ribosomal spacers) and appropriate analytical methods (allelic and infinite-sites approaches; inbreeding and coalescent models) used for ...
Constantine, Clare Colleen
core