Results 111 to 120 of about 180,800 (264)

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

Keefektifan Pemberian Bronkodilator Inhalasi Antara Perangkat Spacer dan Home-made Spacer pada Penderita Penyakit Paru Obstruktif Kronik

open access: yes, 2018
Latar Belakang : Pada Penyakit Paru Obstruktif Kronik (PPOK) kemanjuran klinis terapi bronkodilator yang diberikan melalui spacer maupun home-made spacer pada VEP1 masih kontroversial dan masih tidak ada perbedaan yang signifikan.
Lesmana, Andrean
core  

Radiographic parameters and mechanical complications of articulating vs. non-articulating hip spacers. [PDF]

open access: yesArch Orthop Trauma Surg
Lenz J   +6 more
europepmc   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

CRISPR spacer profiling and prophage mining reveal diverse bacteriophages associated with <i>Streptococcus Mutans</i>. [PDF]

open access: yesJ Oral Microbiol
Chen X   +8 more
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Stent spacer

open access: yes, 2018
A spacer including a first part made from a first shape memory material, and a second part made from a second shape memory ...
Connesson, Nathanael   +4 more
core  

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