Results 21 to 30 of about 46,073 (264)

CRISPR-Cas Systems and the Paradox of Self-Targeting Spacers

Frontiers in Microbiology, 2020
CRISPR-Cas immune systems in bacteria and archaea record prior infections as spacers within each system’s CRISPR arrays. Spacers are normally derived from invasive genetic material and direct the immune system to complementary targets as part of future ...
Franziska Wimmer, Chase L. Beisel, Chase L. Beisel   +2 more
doaj   +1 more source

Comparison of dynamic and static spacers for the treatment of infections following total knee replacement: a systematic review and meta-analysis

Journal of Orthopaedic Surgery and Research, 2022
Background Revision surgery is the most common treatment for patients who develop infection after total knee arthroplasty (TKA). Two types of spacers are often used in revision surgery: dynamic spacers and static spacers.
Jiasheng Tao, Zijian Yan, Bin Pu, Ming Chen, Xiaorong Hu, Hang Dong   +5 more
doaj   +1 more source

Avanços na inaloterapia em pediatria Advances in inhalation therapy in pediatrics

Jornal de Pediatria, 2010
OBJETIVOS: Revisar os artigos mais relevantes a respeito dos aspectos técnicos da terapêutica inalatória, dos inaladores disponíveis e principalmente dos principais avanços obtidos na inaloterapia em pediatria.
Fábio Pereira Muchão, Luiz Vicente Ribeiro Ferreira da Silva Filho   +1 more
doaj   +1 more source

Epidemiological Correlates Of Unmet Need For Contraception In Urban Slum Population [PDF]

Al Ameen Journal of Medical Sciences, 2010
This study was undertaken to find out magnitude and identifying the different variables, which are associated with unmet need for contraception among married women in the age group of 15-44 yrs in an urban slum of Karad, Maharashtra.
Supriya Satish Patil*, MP Durgawale and SR Patil
doaj  

Optimal number of spacers in CRISPR arrays. [PDF]

PLoS Computational Biology, 2017
Prokaryotic organisms survive under constant pressure of viruses. CRISPR-Cas system provides its prokaryotic host with an adaptive immune defense against viruses that have been previously encountered.
Alexander Martynov, Konstantin Severinov, Iaroslav Ispolatov   +2 more
doaj   +1 more source

Bioinformatic Identification of CRISPR–Cas Systems in Leptospira Genus: An Update on Their Distribution Across 77 Species

Pathogens
Leptospirosis is a globally distributed zoonotic disease caused by pathogenic bacteria of the Leptospira genus. Genome editing in Leptospira has been difficult to perform.
Ronald Guillermo Peláez Sánchez, Juanita González Restrepo, Santiago Pineda, Alexandra Milena Cuartas-López, Juliana María Martínez Garro, Marco Torres-Castro, Rodrigo Urrego, Luis Ernesto López-Rojas, Jorge Emilio Salazar Florez, Fernando P. Monroy   +9 more
doaj   +1 more source

The Effect of Bottom Reinforcement Spacers on Reinforced Concrete Structures Loaded by Explosion

Buildings, 2023
Plastic spacers create a linear and systemic weakening of the structure. The extreme loading of the structure tests the structure itself to its load-bearing limit or even locally exceeds this limit, thus revealing all its weak points, which are the ...
Eva Zezulová, Branislav Dubec, Petr Dvořák, Josef Fládr, Klára Cibulová   +4 more
doaj   +1 more source

spacer

, 2014
Citation: 'spacer' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.ST06873 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms. Requests for commercial usage
openaire   +2 more sources

Articulating vs Static Spacers for Native Knee Infection in the Setting of Degenerative Joint Disease

Arthroplasty Today, 2021
Background: Patients with advanced knee arthritis who develop a septic joint are not adequately treated with irrigation and debridement and intravenous antibiotics because of antecedent cartilage damage.
Jessica Hooper, MD, Prerna Arora, MS, Shanthi Kappagoda, MD, James I. Huddleston, III, MD, Stuart B. Goodman, MD, PhD, Derek F. Amanatullah, MD, PhD   +5 more
doaj   +1 more source

Improved bone bonding of hydroxyapatite spacers with a high porosity in a quantitative computed tomography‐image pixel analysis: A prospective 1‐year comparative study of the consecutive cohort undergoing double‐door cervical laminoplasty

JOR Spine, 2020
Laminoplasty using hydroxyapatite (HA) spacers is widely performed in patients with cervical myelopathy. However, spacer dislocation is a critical complication caused by bone absorption and inadequate bone conductivity, and can result in dural damage and
Yoshiki Takeoka, Takashi Yurube, Koichiro Maeno, Yutaro Kanda, Ryu Tsujimoto, Kunihiko Miyazaki, Yuji Kakiuchi, Shingo Miyazaki, Zhongying Zhang, Toru Takada, Kotaro Nishida, Minoru Doita, Ryosuke Kuroda, Kenichiro Kakutani   +13 more
doaj   +1 more source