Results 51 to 60 of about 2,220,122 (313)

ATLANTIS IN SPAIN IV

open access: yesBulletin of the Geological Society of Greece, 2017
Many analysts in the past faced Atlantis’ main city with the same way they faced his idealised concentric cities which he described in his dialogues. However, Atlantis’ concentric city has a marked difference which is recognisable if the analyst has geological knowledge.
openaire   +13 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Case translation: Spain [PDF]

open access: yes, 2017
Case citation: STS 2047/2015, Tribunal Supremo, Sala de lo Penal (Supreme Court, Criminal Chamber), 19 May 2015, translated by Patricia Ayodeji Spain; sexual abuse of a minor; communications via social networks ...
Case Translations:, Spain
core   +1 more source

De Flora Valentina, XVIII [PDF]

open access: yesFlora Montiberica, 2019
Se comunican los hallazgos de una serie de especies de plantas vasculares detectadas en la Comunidad Valenciana, que resultan novedosas o poco conocidas en la misma.
Gonzalo MATEO SANZ
doaj  

Historia(s) en movimiento: La Primera Guerra Mundial como evento de medios populares en España y México / History(ies) in motion: The First World War as popular media event in Spain and Mexico

open access: yesBoletín de Literatura Oral, 2019
The First World War was a global media event. Several magazines with different aims and takes reported about the occurencies in texts and images. This also was the case in Spain and Mexico. The information was disseminated both in
Ricarda Musser
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Desarrollo de efectos cerámicos como acabados superficiales, mediante tecnología de inyección digital

open access: yesBoletín de la Sociedad Española de Cerámica y Vidrio, 2012
Ferro Spain SA has tackled the practical viability of tile surfaces decoration by means of applying layers of reduced thickness by means of the use of digital injection technology by inkjet and, specifically, relating to effects and superficial finishes ...
Spain S.A., Ferro
doaj  

Neuroimaging features of immune-related adverse events due to immune checkpoint inhibitor therapy

open access: yesInsights into Imaging
Immune checkpoint inhibitors, a type of intravenous immunotherapy targeting T cells, are being increasingly used in cancer treatment. They work by increasing the immune system’s response to tumour cells, through blockade of inhibitory “checkpoint ...
Arian Lasocki, Lavinia Spain
doaj   +1 more source

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