Results 51 to 60 of about 3,087,038 (313)

Does Board Gender Diversity Influence Financial Performance? Evidence from Spain

Journal of Business Ethics, 2015
In recent years, several countries have enacted guidelines and/or mandatory laws to increase the presence of women on the boards of companies. Through these regulatory interventions, the aim is to eradicate the social and labor grievances that women have
Nuria Reguera-Alvarado, P. de Fuentes, J. Laffarga   +2 more
semanticscholar   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Schooling in Spain and in the province of Jaén in the first half of the 19th century

Cabás, 2023
El título de nuestra investigación responde al análisis histórico de una de las parcelas que mayor interés despierta: la educación. El objeto de nuestro trabajo es analizar el desarrollo de la enseñanza primaria en España, comparándolo con lo que ...
Rivera, Blas
doaj   +1 more source

Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

FEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual, Marta Navarro‐Gutiérrez, Verónica Romero‐Albillo, Raquel Jiménez‐Sánchez   +3 more
wiley   +1 more source

De Flora Valentina, XVIII [PDF]

Flora Montiberica, 2019
Se comunican los hallazgos de una serie de especies de plantas vasculares detectadas en la Comunidad Valenciana, que resultan novedosas o poco conocidas en la misma.
Gonzalo MATEO SANZ
doaj  

Historia(s) en movimiento: La Primera Guerra Mundial como evento de medios populares en España y México / History(ies) in motion: The First World War as popular media event in Spain and Mexico

Boletín de Literatura Oral, 2019
The First World War was a global media event. Several magazines with different aims and takes reported about the occurencies in texts and images. This also was the case in Spain and Mexico. The information was disseminated both in
Ricarda Musser
doaj   +1 more source

Prevalence of diabetes mellitus and impaired glucose regulation in Spain: the Di@bet.es Study

Diabetologia, 2011
Aims/hypothesisThe Di@bet.es Study is the first national study in Spain to examine the prevalence of diabetes and impaired glucose regulation.MethodsA population-based, cross-sectional, cluster sampling study was carried out, with target population being
F. Soriguer, A. Goday, A. Bosch-Comas, E. Bordiú, A. Calle-Pascual, R. Carmena, R. Casamitjana, L. Castaño, C. Castell, M. Catalá, E. Delgado, J. Franch, S. Gaztambide, J. Girbes, R. Gomis, Galder Gutiérrez, A. López-Alba, M. Martínez-Larrad, E. Menéndez, I. Mora-Peces, E. Ortega, G. Pascual-Manich, G. Rojo-Martínez, M. Serrano-Ríos, S. Valdés, J. Vázquez, J. Vendrell   +26 more
semanticscholar   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source