Results 61 to 70 of about 2,220,122 (313)
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Trophic categorization in the Rías Baixas (NW Spain): nutrients in water and in macroalgae
Scientia Marina, 2006 Marine eutrophication caused by an excess supply of nutrients is a serious problem in many coastal areas throughout the world. In the present study we used the capacity of macroalgae (Ulva and Enteromorpha) to integrate the nutrient regime of a water ...
Rubén Villares, Alejo Carballeira
doaj +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Anales del Jardín Botánico de Madrid, 1999 An integral palaeobotanical study (macro- and microflora) has been done of the Salanca ravine outcrop. This place is located in the región of la Cerdaña (Lérida province, Spain), which constitutes an Upper Miocene lacustrine basin from Eastern Pyrenees ...
Eduardo Barrón
doaj +1 more source
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
FEBS Open Bio, EarlyView.Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
Interview with Frances Lander Spain - OH 081 [PDF]
, 1980 In her April 26, 1980 interview with Arnold M. Shankman, the 1925 graduate of Winthrop University, Frances Lander Spain, discusses her life and accomplishments.
Spain, Frances Lander
core +1 more source
The Sums and Products of Commuting AC-Operators
International Journal of Industrial Engineering and Production Research, 2007 : In this paper, we exhibit new conditions for the sum of two commuting AC-operators to be again an AC-operator. In particular, this is satisfied on Hilbert space when one of them is a scalar-type spectral operator.
M.B Ghaemi, p. Spain
doaj
Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus
FEBS Open Bio, EarlyView.BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima +7 more
wiley +1 more source
Advancing Age Modulates Associations Between Cognitive Impairment and Brain Volumes in Early MS
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Introduction Cognitive impairment is common in multiple sclerosis (MS), but manifestations following the first demyelinating event are relatively unexplored. We investigated cross‐sectional associations between magnetic resonance imaging (MRI)–derived brain volumes and the presence of cognitive impairment outcomes five years after the first ...
Piriyankan Ananthavarathan +14 more
wiley +1 more source