Results 61 to 70 of about 3,824,074 (333)

Breaking New Ground in Spain: A General Description of the Spanish Employment System [PDF]

open access: yes, 2006
[Excerpt] This introductory summary of employment law in Spain focuses primarily on labor law, but also addresses basic aspects of social security law and immigration law, all of which are closely related. This summary is not intended to be comprehensive
Baker & McKenzie
core   +1 more source

Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation

open access: yesMolecular Oncology, EarlyView.
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides   +13 more
wiley   +1 more source

Territory, tourism and local products. The extra virgin oil's enhancement and promotion: a benchmarking Italy-Spain

open access: yesTourism and Hospitality Management, 2013
Purpose – This paper intends to highlight how local tourism development is strongly oriented towards policy development based on the combination typical product-territory, in particular extra virgin olive oil, which assigns value to identity, social ...
Paola de Salvo   +3 more
doaj   +1 more source

The Performativity of State Non-Recognition in Sports: The Case of Spain over Kosovo

open access: yesPolitics in Central Europe, 2021
This article focuses on the use of sport by the Spanish Government to perform its non-recognition of Kosovo’s statehood. Our main goal is to analyse the practices and narratives through which Spain’s public authorities have carried out this policy in the
Gutiérrez-Chico Fernando   +1 more
doaj   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

open access: yesMolecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza   +3 more
wiley   +1 more source

The Sums and Products of Commuting AC-Operators

open access: yesInternational Journal of Industrial Engineering and Production Research, 2007
: In this paper, we exhibit new conditions for the sum of two commuting AC-operators to be again an AC-operator. In particular, this is satisfied on Hilbert space when one of them is a scalar-type spectral operator.
M.B Ghaemi, p. Spain
doaj  

Work Organisation and Innovation - Case Study: Kellogg, Spain [PDF]

open access: yes, 2013
[Excerpt] Kellogg Spain, a subsidiary of the multinational with the same name, started activity over 30 years ago. Currently the company has around 130 employees who are responsible for the market in the Iberia region (Spain and Portugal).
Ortigão, Manuel
core   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

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