Results 71 to 80 of about 1,311,589 (257)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Hemispheric differences in ozone across the stratosphere–troposphere exchange region [PDF]

Atmospheric Chemistry and Physics
Ozone changes in the upper troposphere–lower stratosphere (UTLS) resulting from dynamical and chemical processes strongly affect the atmosphere's radiative forcing. This study analyzed intra- and inter-hemispheric ozone differences in the UTLS within the
R. J. Seguel, R. J. Seguel, C. Opazo, C. Opazo, Y. Cohen, O. R. Cooper, L. Gallardo, L. Gallardo, B.-M. Sinnhuber, F. Obersteiner, A. Zahn, P. Hoor, S. Rohs, A. Marsing   +13 more
doaj   +1 more source

اثر بتائین بر عملکرد و ریخت‌شناسی روده کوچک جوجه‌های گوشتی تحت تنش گرمایی [PDF]

تحقیقات تولیدات دامی, 2017
این تحقیق به منظور بررسی تاثیر بتائین بر رشد، وزن و طول بخش­های مختلف روده و ریخت­شناسی روده کوچک در جوجه­های گوشتی تحت تنش گرمایی انجام گرفت. دویست قطعه جوجه نر یک روزه سویه راس در قالب طرح کاملاً تصادفی با چهار تیمار و پنج تکرار به ازای هر تیمار و 10 ...
زاهد عزیز مسگری, محسن دانشیار, علی میرزا آقازاده, غلامرضا نجفی, فرهاد فرهنگ پژوه   +4 more
doaj   +1 more source

The Star Clusters in the Irregular Galaxy NGC 4449 [PDF]

, 2000
We examine the star clusters in the irregular galaxy NGC 4449. We use a near-infrared spectrum and broad-band images taken with the HST to place a limit of 8--15 Myrs on the age of the bright central ojbect in NGC 4449.
Andrea E. Gelatt, Bajaja E., Bica E., Deidre A. Hunter, J. S. Gallagher, Larsen S. S., Noguchi M., Olofsson K., Poulain P., Quinn T., Theis C.   +10 more
core   +2 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Preparation and Evaluation of Dapagliflozin Propanediol Monohydrate-Loaded Transferosomal Dispersion for Transdermal Delivery

Iraqi Journal of Pharmaceutical Sciences
The transdermal route of drug delivery has received significant attention in pharmaceutical research due to its ability to overcome many challenges associated with oral medication administration, including the ability to bypass first-pass metabolism ...
Mohsin Hussein Abdulameer, Nidhal Khazaal Maraie   +1 more
doaj   +1 more source

Research on atmospheric temperature fine measurements from the near surface to 60 km altitude based on an integrated lidar system [PDF]

Atmospheric Measurement Techniques
Accurate measurement of atmospheric temperature profiles from the surface to the stratosphere is crucial for understanding atmospheric dynamics and climate processes.
Z. Wang, T. Guo, T. Guo, X. Li, X. Li, C. Chen, D. Liu, L. Qu, H. Li, H. Li, X. Wang   +10 more
doaj   +1 more source

On the reliability of the so far performed tests for measuring the Lense-Thirring effect with the LAGEOS satellites

, 2005
In this paper we will show in detail that the performed attempts aimed at the detection of the general relativistic Lense-Thirring effect in the gravitational field of the Earth with the existing LAGEOS satellites are often presented in an optimistic and
Allison, Casotto, Cheng, Ciufolini, Ciufolini, Ciufolini, Ciufolini, Ciufolini, Ciufolini, Ciufolini, Ciufolini, Eanes, Everitt, Gruber, Iorio, Iorio, Iorio, Iorio, Iorio, Iorio, Iorio, Iorio, Iorio, Iorio, Iorio, Iorio, Iorio, Iorio, Kaula, Lense, Lucchesi, Lucchesi, Lucchesi, Lucchesi, Lucchesi, Lucchesi, Lämmerzahl, Lämmerzahl, Mashhoon, Nordtvedt, Pavlis, Pavlis, Reigber, Reigber, Reigber, Reigber, Ries, Ruggiero, Schiff, Schäfer, Tapley, Tapley, Vespe, Will   +53 more
core   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Pengaruh Waktu Reaksi dan Suhu Pada Proses Ozonasi Terhadap Penurunan Warna, COD dan BOD Air Limbah Industri Tekstil

Jurnal Kimia dan Kemasan, 2011
Air limbah industri tekstil pada umumnya bersifat alkali, berbau, berwarna, panas dan mempunyai TSS, BOD dan COD yang tinggi. Oleh karena itu selain berwarna, air limbah industri tekstil mengandung bahan-bahan organik dan logam berat yang berbahaya bagi ...
Emmy Ratnawati
doaj   +1 more source