Results 41 to 50 of about 285,519 (260)

Curcumin effects on myeloperoxidase, interleukin-18 and matrix metalloproteinase-9 inflammatory biomarkers in patients with unstable angina: A randomized clinical trial [PDF]

Avicenna Journal of Phytomedicine, 2019
Objective: Inflammation along with oxidative stress plays an important role in the development, progression, instability and rupture of coronary atherosclerotic plaques.
Amir hooshang Mohammad pour, Mostafa Dastani, Roshanak Salari, Sohrab Radbin, Soghra Mehri, Maryam Ghorbani, Asieh Karimani, Masoumeh Salari   +7 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Combination of SPH and SP80 prolongs the lifespan of Bacillus subtilis natto to enhance industrial menaquinone-7 biosynthesis

Frontiers in Microbiology
Menaquinone-7 (MK-7) production from renewable feedstocks using Bacillus subtilis natto provides a promising pathway toward sustainability. However, MK-7 yields are often limited by poor microbial cell viability.
Liu-xiu Hu, Liu-xiu Hu, Yu Chen, Yu Chen, Hong-ping Zhou, Wei Tao, Xu-li Gao, Chuan-chao Wu, Chuan-chao Wu, Hui-min Zhang, Hui-min Zhang, Ru-meng Han, Ru-meng Han, Yu-qi Li, Yan Liu, Yan Liu, Yan Liu   +16 more
doaj   +1 more source

Effect of Span-80 to Moisture Resistance of Near-infrared Curing 3D Printing Sodium Silicate Foundry Sands [PDF]

Archives of Foundry Engineering
In this work, a new method of near-infrared curing 3D printing sodium silicate sands (NIRC3DPSSS) driven by photovoltaic cells was proposed, and the Span-80 moisture resistance modifier was studied.
Ao Xue, Yuhan Tang, Yao Li, Weihong Dai, Jijun Lu, Huafang Wang   +5 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Microencapsulation of Riboflavin (Vitamine B2) using Alginate and Chitosan : Effect of Surfactant Span 80 upon Microcapsule Diameter

Equilibrium, 2018
Riboflavin (vitamin B2) plays an important role in the growth and maintenance of human metabolism. Riboflavin is the highly sensitive and unstable to environmental influences such as light, reducing agents and pH.
YC. Danarto, Rochmadi Rochmadi, Budhijanto Budhijanto   +2 more
doaj   +1 more source

FORMULASI EMULGEL TRANSDERMAL ASETOSAL MENGGUNAKAN SPAN 80 KOMBINASI TWEEN 80 SEBAGAI EMULGATOR

JURNAL FARMASI GALENIKA, 2020
Asam asetil salisilat atau yang lebih dikenal dengan asetosal atau aspirin merupakan senyawa yang memiliki khasiat sebagai analgesik, antipiretik, dan anti inflamasi pada penggunaan dosis besar. Saat ini asetoal dengan dosis rendah merupakan antiplatelet yang sering digunakan pada pasien dengan penyakit jantung koroner maupun pada hipertensi berat ...
openaire   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

FORMULASI MIKROEMULSI MINYAK DALAM AIR (O/W) YANG STABIL MENGGUNAKAN KOMBINASI TIGA SURFAKTAN NON IONIK DENGAN NILAI HLB RENDAH, TINGGI DAN SEDANG Stable O/W Microemulsion Formulation Using Combination of Three Nonionic Surfactants with Low, High and Med

Agritech, 2012
The aim of this research was to determine the proportion of oil, surfactant and water which could produce a stable O/W microemulsion using combination of three nonionic surfactants with low, high and medium HLB values; and to determine the role of ...
Sih Yuwanti, Sri Raharjo, Pudji Hastuti, Supriyadi Supriyadi   +3 more
doaj   +1 more source