Results 61 to 70 of about 285,519 (260)

Development of Ibuprofen Loaded Solid Dispersion with Improved Dissolution Using Tween 80 & Span 80

open access: yesInternational Journal of Pharmaceutical and Life Sciences, 2012
To develop a novel dosage form of ibuprofen loaded solid dispersion with improved dissolution, formulations were developed using mixture of tween 80 & span 80 with a sugar such as dextrose, icing sugar. Percentage of tween 80 & span 80 was 10% & 5%, 7.5% & 7.5%, 5% & 10% and amount of sugar was fixed (1.2 g).
Asma Huq, Naila Shahrin
openaire   +2 more sources

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

open access: yesMolecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant   +7 more
wiley   +1 more source

PEMBUATAN BUBUK SARI BUAH MARKISA DENGAN METODE “Foam-Mat Drying” (The Making Markisa Juice Powder using Foam Mat Drying Method)

open access: yesJurnal Teknologi Pangan, 2015
Markisa juice is a product that has a save relatively short time. One of the efforts to extend the save and simplify the transport process of markisa juice was by drying using a Foam mat drying method , thus obtained powder extract of markisa fruit ...
Mulyani T, Yulistiani dan Nopriyanti M JURNAL TEKNOLOGI PANGAN
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Investigating the Effect of Coated Lipid Nano Particles of Spironolactone with Chitosan on Their Properties

open access: yesJournal of Mazandaran University of Medical Sciences, 2018
Background and purpose: Solid lipid nanoparticles are in the colloid carriers. The benefits of these drug carriers are the controlled release of the drug and the protection of the drug being loaded.
Reza Enayatifard   +7 more
doaj  

Preparation and Evaluation of Dapagliflozin Propanediol Monohydrate-Loaded Transferosomal Dispersion for Transdermal Delivery

open access: yesIraqi Journal of Pharmaceutical Sciences
The transdermal route of drug delivery has received significant attention in pharmaceutical research due to its ability to overcome many challenges associated with oral medication administration, including the ability to bypass first-pass metabolism ...
Mohsin Hussein Abdulameer   +1 more
doaj   +1 more source

OPTIMASI KOMPOSISI TWEEN 80 DAN SPAN 80 SEBAGAI EMULGATOR DALAM REPELAN MINYAK ATSIRI DAUN SERE (Cymbopogon citratus (DC) Stapf) TERHADAP NYAMUK Aedes aegypti BETINA PADA BASIS VANISHING CREAM DENGAN METODE SIMPLEX LATTICE DESIGN

open access: yesPharmaciana, 2012
The disease of Dengue hemorrhagic fever (DHF) is caused by the bite of female Aedes aegypti mosquito. Cream of repelan sere leaf essential oils can be used to prevent mosquito bites.
Endah Nurlaela   +2 more
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline

open access: yesFEBS Open Bio, EarlyView.
Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey   +4 more
wiley   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

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