Results 31 to 40 of about 2,088,425 (263)
Clinical Course and Impact of Breaks in Therapy for Children With Relapsed/Refractory Solid Tumors
Pediatric Blood &Cancer, EarlyView.ABSTRACT Introduction Pediatric relapsed or refractory (R/R) solid tumors carry a dismal prognosis, and postrelapse patient experiences are not well described. We present postrelapse outcomes, including number of R/R events and subsequent therapy regimens.
Matthew T. McEvoy +5 more
wiley +1 more source
Russian Journal of LinguisticsThe realization of the speech act of inviting is susceptible to situational and sociocultural context. To issue an appropriate invitation, speakers must respect cultural norms and use politeness strategies accepted in each communicative culture.
Elena Shorokhova, Palma Peña-Jiménez
doaj +1 more source
Cuadernos AISPI, 2022 La metáfora en la conformación del léxico médico de la Guatemala ilustrada: algunos ejemplos de la Instrucción sobre el modo de practicar la inoculación de la viruelas de José Felipe ...
José Luis Ramírez Luengo
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Treatment Decision‐Making Roles and Preferences Among Adolescents and Young Adults With Cancer
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Decision‐making (DM) dynamics between adolescents and young adults (AYAs) with cancer, parents, and oncologists remain underexplored in diverse populations. We examined cancer treatment DM preferences among an ethnically and socioeconomically diverse group of AYAs and their parents.
Amanda M. Gutierrez +14 more
wiley +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
A fraseoloxía da música na vida cotiá. Un estudo contrastivo (alemán - español) [PDF]
Cadernos de Fraseoloxía Galega, 2007 No presente artigo baseámonos na linguaxe musical como medio para escudriñar na psicoloxía humana a través da linguaxe fraseolóxica. Noutras palabras, examinamos determinados aspectos coma o carácter, as relacións e as emocións humanas tomando a música
Ana Mansilla
doaj
Axiological aspects of teaching Spanish in the Soviet Union
Российский технологический журнал, 2022 Objectives. The paper analyzes core axiological aspects of Spanish teaching in higher educational institutions of the Soviet Union from the 1930s to the early 1980s based on various sources including textbooks, tutorials, etc. Methods. The study is based
E. V. Novoselova +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Heritage Language and Linguistic Theory
Frontiers in Psychology, 2015 This paper discusses a common reality in many cases of multilingualism: heritage speakers, or unbalanced bilinguals, simultaneous or sequential, who shifted early in childhood from one language (their heritage language) to their dominant language (the ...
Gregory eScontras +2 more
doaj +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source