Results 51 to 60 of about 4,314,438 (309)

Beryllium Bonding in the Light of Modern Quantum Chemical Topology Tools [PDF]

open access: yes, 2018
We thank the Spanish MINECO, grant CTQ2015-6.5790-P, the FICyT, grant GRUPIN14-049, and the European Union FEDER for funding. F.J.-G.
Casals Sainz, José Luis   +4 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Measures of narrative performance in Spanish-speaking children on the test of narrative language-Spanish [PDF]

open access: yes, 2014
textIn the field of speech-language pathology, there is an increasing need for valid and appropriate assessment measures for Spanish-speaking students that can reliably be given by examiners with a wide range of Spanish knowledge and scoring experience ...
Perme, Amanda Lee
core  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Task-based elementary Spanish in rural Indiana: A practice-based collaboration

open access: yesStudies in Second Language Learning and Teaching
Spanish is the second most spoken language in the United States and the most taught additional language (L2) in elementary-level schools. However, the amount and type of access differs according to the resources available.
Laura Gurzynski-Weiss   +3 more
doaj   +1 more source

A destressing "deafness" in French? [PDF]

open access: yes, 1997
French is a language in which accent is mandatory on the last syllable of every content word. In contrast, Spanish uses accent to distinguish different lexical items (e.g., b'ebe vs beb'e).
Dupoux, E.   +3 more
core   +4 more sources

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Spanish Spanish

open access: yesCIENCIA UNEMI
Resumen En la presente investigación se va analizar el control de convencionalidad, que es un concepto teórico-jurídico desarrollado por la Corte Interamericana de Derechos Humanos (Corte IDH), cuyo objetivo principal es asegurar la conformidad del derecho nacional con el derecho internacional de los derechos humanos.
Venegas Guayasamín, Bryan Andrés   +3 more
openaire   +3 more sources

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

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