Results 61 to 70 of about 3,195,608 (305)

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Publishing abroad: fair trade or short sell for non-English-speaking authors? a Spanish study [PDF]

open access: yes, 1997
We investigated the integration into the international scientific literature of articles published by researchers at the University of Granada (Spain) between 1976 and 1987, in journals published outside of Spain.
Jimenez-Contreras, Evaristo
core   +1 more source

Metaphor in Spanish L2 and Heritage Language Learners’ Speech: How Does it Compare?

open access: yesDarnioji daugiakalbystė, 2019
One way in which language practitioners and researchers have furthered our understanding of heritage language learners’ linguistic abilities has been to compare them to L2 learners.
Tocaimaza-Hatch Cecilia
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

The Use of Spanish Light Verb Constructions in the Advocate General’s Opinions of the Court of Justice of the European Union

open access: yesDarnioji daugiakalbystė
Over the past few decades, increasing attention has been devoted towards the study of formulaic language, both in Lithuania and abroad. It is assumed that stable word combinations, rather than single words, are preferred in speaking and translating ...
Serapinienė Gabija
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Comparative Analysis of Contextual Usage of the Lexemes мiръ / миръ / мир and their translations into Spanish

open access: yesRUDN Journal of Language Studies, Semiotics and Semantics
In the critical literature devoted to the L.N. Tolstoy’s novel «War and Peace», the contradictory contexts of usage of the lexemes мiръ / миръ / мир and their relation to homonymy, were repeatedly discussed.
Marina O. Chichina
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Achegas a un dicionario de refráns galego-castelán, castelán-galego [PDF]

open access: yesCadernos de Fraseoloxía Galega, 2003
Monográfico. Este terceiro número de “Cadernos de Fraseoloxía Galega” é unha monografía da autoría de María do Rosario Soto Arias. Nela ofrécenos equivalencias castelás duns 4.400 refráns galegos e as equivalencias galegas duns 4.100 refráns casteláns ...
María Rosario Soto Arias
doaj  

Afro-Peruvian Spanish [PDF]

open access: yes, 2015
The present work not only contributes to shedding light on the linguistic and socio-historical origins of Afro-Peruvian Spanish, it also helps clarify the controversial puzzle concerning the genesis of Spanish creoles in the Americas in a broader sense.
openaire   +4 more sources

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