Results 21 to 30 of about 135,087 (312)

Improved Outcomes for Older Children, Adolescents, and Young Adults With Neuroblastoma in the Post‐Immunotherapy Era: An Updated Report From the International Neuroblastoma Risk Group

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background We describe clinical and biologic characteristics of neuroblastoma in older children, adolescents, and young adults (OCAYA); describe survival outcomes in the post‐immunotherapy era; and identify if there is an age cut‐off that best discriminates outcomes.
Rebecca J. Deyell   +14 more
wiley   +1 more source

Los «exiliados económicos». La nueva emigración española a América Latina y el Caribe (2008-2016) [PDF]

open access: yesRevista Iberoamericana de Estudios de Desarrollo, 2018
The article analyzes the Spanish emigration to Latin America between 2008 and 2015, with the prospect to approach a quantitative reality, of understanding the demographic profile of the new Spanish emigrants to Latin America, the causes of their ...
RODRÍGUEZ-FARIÑAS, Jara
doaj   +1 more source

Characterizing Parental Concerns About Lasting Impacts of Treatment in Children With B‐Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background B‐acute lymphoblastic leukemia (B‐ALL) is the most common pediatric cancer, and while most children in high‐resource settings are cured, therapy carries risks for long‐term toxicities. Understanding parents’ concerns about these late effects is essential to guide anticipatory support and inform evolving therapeutic approaches ...
Kellee N. Parker   +7 more
wiley   +1 more source

The Spanish Cooperation in Latin America and the Caribbean: Training Actions in the Field of Disaster Risk Reduction

open access: yesRevista de Estudios Latinoamericanos sobre Reducción del Riesgo de Desastres, 2023
The Sendai Framework for Disaster Risk Reduction specifies that international cooperation for developing countries should be significantly improved through adequate and sustainable support that complements the measures taken at the national level for its
José Pastrana Huguet   +1 more
doaj   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

La gestión de proyectos como materia en los estudios universitarios de Información y Documentación en Iberoamérica

open access: yesBiD: Textos Universitaris de Biblioteconomia i Documentació, 2014
Objetivos: analizar la situación de la gestión de proyectos como materia en los estudios universitarios de grado y posgrado (máster) de Información y Documentación en Iberoamérica (Argentina, Bolivia, Brasil, Chile, Colombia, Costa Rica, Cuba, Ecuador ...
Cobo Serrano, Silvia   +1 more
doaj   +1 more source

Canning and Spanish America [PDF]

open access: yesTransactions of the Royal Historical Society, 1904
In a letter to Hookham Frere, on January 8, 1825, Canning spoke of the recognition of Mexico and Colombia as 'an act which will make a change in the face of the world almost as great as that of the discovery of the continent now set free. The Allies will fret; but they will venture no serious remonstrance. France will fidget; but it will be with a view
openaire   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

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