Results 21 to 30 of about 134,557 (312)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Ongoing evidence indicates increased risk of sarcopenic obesity among children and young people (CYP) with acute lymphoblastic leukemia (ALL), often beginning early in treatment, persisting into survivorship. This review evaluates current literature on body composition in CYP with ALL during and after treatment.
Lina A. Zahed +5 more
wiley +1 more source
Los «exiliados económicos». La nueva emigración española a América Latina y el Caribe (2008-2016) [PDF]
Revista Iberoamericana de Estudios de Desarrollo, 2018 The article analyzes the Spanish emigration to Latin America between 2008 and 2015, with the prospect to approach a quantitative reality, of understanding the demographic profile of the new Spanish emigrants to Latin America, the causes of their ...
RODRÍGUEZ-FARIÑAS, Jara
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background We describe clinical and biologic characteristics of neuroblastoma in older children, adolescents, and young adults (OCAYA); describe survival outcomes in the post‐immunotherapy era; and identify if there is an age cut‐off that best discriminates outcomes.
Rebecca J. Deyell +14 more
wiley +1 more source
Early swelling response to phytohemagglutinin is lower in older toads [PDF]
PeerJ, 2018 The effects of age on performance of life-history traits are diverse, but a common outcome is senescence, an irreversible deterioration of physical and physiological capabilities of older individuals.
Francisco Javier Zamora-Camacho +1 more
doaj +2 more sources
FEBS Letters, EarlyView.Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer +7 more
wiley +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
BiD: Textos Universitaris de Biblioteconomia i Documentació, 2014 Objetivos: analizar la situación de la gestión de proyectos como materia en los estudios universitarios de grado y posgrado (máster) de Información y Documentación en Iberoamérica (Argentina, Bolivia, Brasil, Chile, Colombia, Costa Rica, Cuba, Ecuador ...
Cobo Serrano, Silvia +1 more
doaj +1 more source
Canning and Spanish America [PDF]
Transactions of the Royal Historical Society, 1904 In a letter to Hookham Frere, on January 8, 1825, Canning spoke of the recognition of Mexico and Colombia as 'an act which will make a change in the face of the world almost as great as that of the discovery of the continent now set free. The Allies will fret; but they will venture no serious remonstrance. France will fidget; but it will be with a view
openaire +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source