Results 51 to 60 of about 4,320,003 (305)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Linear Boltzmann Equation for Solute Dispersion in Heterogeneous Media Under Non-Ergodic Conditions

open access: yesARC Geophysical Research
We study solute dispersion under non-ergodic conditions using a Boltzmann equation for the evolution of the joint distribution of the position and speed of solute particles in steady spatially heterogeneous flow fields.
Marco Dentz, Arash Massoudieh
doaj   +1 more source

Voices of the Past, Echoes of the Present: The Influence of the Amerindian Languages of Latin America on Modern Spanish

open access: yesИбероамериканские тетради
The indigenous languages of Latin America, which have become part of the historical and cultural heritage, not only reflect the centuries-old traditions and worldview of the peoples of the region, but also have a direct influence on the grammatical and ...
A. N. Gurov
doaj   +1 more source

Espacios globales y espacios locales: en busca de nuevos enfoques a los conflictos ambientales. Panorámica sobre Sudamérica y Chile, 2010-2015

open access: yesRevista de Estudios Sociales, 2017
The article oversees the Environmentas Conflicts (CA as per its Spanish acronym) in South America and Chile caught through the confrontation of different conceptual spaces, but rising from the same material space.
Aaron Napadensky, Ricardo Azocar
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Government in Spanish America

open access: yesAmerican Political Science Review, 1914
Although the events of the recent Mexican tragedy cannot be seen today in as clear light as that which will be thrown on them for the next generation, still the political history of the communities established by Spain in America furnishes a certain measure of enlightment.
openaire   +2 more sources

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Hispanic America in Linguistic and Regional Studies: New Educational Encyclopedia

open access: yesИбероамериканские тетради
Book Review: E.V. Astakhova, Yu.V. Davtyan, E.V. Kriukova. Spanish-speaking countries of Latin America and the Caribbean: national images. History. Culture. Language. Textbook on linguistic and regional studies / Ed. by V. Iovenko.
M. M. Raevskaya
doaj   +1 more source

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