Results 51 to 60 of about 4,320,003 (305)
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Linear Boltzmann Equation for Solute Dispersion in Heterogeneous Media Under Non-Ergodic Conditions
We study solute dispersion under non-ergodic conditions using a Boltzmann equation for the evolution of the joint distribution of the position and speed of solute particles in steady spatially heterogeneous flow fields.
Marco Dentz, Arash Massoudieh
doaj +1 more source
The indigenous languages of Latin America, which have become part of the historical and cultural heritage, not only reflect the centuries-old traditions and worldview of the peoples of the region, but also have a direct influence on the grammatical and ...
A. N. Gurov
doaj +1 more source
The article oversees the Environmentas Conflicts (CA as per its Spanish acronym) in South America and Chile caught through the confrontation of different conceptual spaces, but rising from the same material space.
Aaron Napadensky, Ricardo Azocar
doaj +1 more source
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Although the events of the recent Mexican tragedy cannot be seen today in as clear light as that which will be thrown on them for the next generation, still the political history of the communities established by Spain in America furnishes a certain measure of enlightment.
openaire +2 more sources
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Spatial biology in cancer epigenetics
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Hispanic America in Linguistic and Regional Studies: New Educational Encyclopedia
Book Review: E.V. Astakhova, Yu.V. Davtyan, E.V. Kriukova. Spanish-speaking countries of Latin America and the Caribbean: national images. History. Culture. Language. Textbook on linguistic and regional studies / Ed. by V. Iovenko.
M. M. Raevskaya
doaj +1 more source

