Results 41 to 50 of about 537,528 (303)
Métricas del ritmo aplicadas al estudio dialectológico del español
Estudios de Fonética Experimental, 2022 This paper reviews previous studies about dialectal variation of rhythm in Spanish and aims to analyse possible differences among Spanish spoken in Andalusia, Madrid, and Galicia.
doaj
Borealis: An International Journal of Hispanic Linguistics, 2019 El presente trabajo ofrece una primera descripción del comportamiento del cuantificador cadas –en relación a su forma estándar cada– cuando aparece antepuesto a un sustantivo plural, esto es, a partir de las propiedades formales del elemento que acompaña.
Enrique Pato
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AN EXPERIMENTAL INVESTIGATION OF VARIATION IN SPANISH DIMINUTIVES.
Dialectologia, 2019 In an online survey, 656 Spanish speakers from 21 countries were asked to select between the long and short diminutive forms of 100 base words (e.g. novio > novito, noviecito). The influence of the base word, the base word’s frequency, and the country of origin, gender, age, and educational level of the speakers were assessed.
openaire +2 more sources
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Historia de una excepción perfecta
Recherches, 2019 In this study, we carry out a detailed analysis of current grammatical variation phenomena related to the Spanish pretérito perfecto compuesto (present perfect) which we consider to be a major grammaticalization process, as we will show.
Carlos Soler Montes
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Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Polylinguality and Transcultural Practices, 2014 The article deals with the analysis of the macro- and microstructures of the Russian-Spanish conversation guides from the perspective of the Mexican national variation of the Spanish language, to the study of the lexical-semantic divergence when compared
S A Iakovleva
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Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source