Results 91 to 100 of about 1,987,967 (281)

Rabatt-Spar-Verein, Pfg. 20, Frankfurt

open access: yes
RABATT-SPAR-VEREIN, PFG. 20, FRANKFURT Rabatt-Spar-Verein, Pfg. 20, Frankfurt ( -
Rabatt-Spar-Verein
core   +1 more source

ZBTB18 Dysfunction Promotes Neuropathic Pain via CHD4‐based Epigenetic Disinhibition of CLIC1 Channels in Sensory Neurons

open access: yesAdvanced Science, EarlyView.
In this study, we identify a novel functional role of ZBTB18 in regulating trigeminal‐mediated neuropathic pain. Nerve injury reduces ZBTB18 in trigeminal ganglion neurons, impairing CHD4/NuRD recruitment and de‐repressing Clic1. Elevated CLIC1 enhances chloride channel activity and neuronal hyperexcitability, thereby driving pain.
Shoupeng Wang   +11 more
wiley   +1 more source

Potential of Nanoparticle‐Based Phototherapies for Future Treatment of Uveal Melanoma

open access: yesAdvanced Science, EarlyView.
This review evaluates nanoparticle‐based phototherapies for uveal melanoma, highlighting emerging strategies to enhance tumor targeting, light delivery, and treatment precision. Preclinical data indicate improved efficacy and reduced toxicity, supporting their potential to enhance localized treatment and future translational advances. (Generated by the
Emilie Lambert   +8 more
wiley   +1 more source

Consumer's perception about Spar brand products

open access: yes, 2015
Szakdolgozatom témájául a Spar saját márkás termékek fogyasztói megítélését választottam. Szekunder és primer kutatást végeztem. Szekunder kutatásom során szakmai irodalom segítségével bemutattam a kereskedelmet, a terméket, márkát, különböző fogyasztói ...
Hernyák, Hanna
core  

Nonlinear System Identification via Basis Functions Based Time Domain Volterra Model

open access: yesMATEC Web of Conferences, 2014
This paper proposes basis functions based time domain Volterra model for nonlinear system identification. The Volterra kernels are expanded by using complex exponential basis functions and estimated via genetic algorithm (GA).
Yazid Edwar   +4 more
doaj   +1 more source

The Cancer Cell Metabolic Reprogramming Remodels the Tumor Microenvironment: Molecular Mechanisms and Therapeutic Strategies

open access: yesAdvanced Science, EarlyView.
This review elucidates how cancer cell metabolic reprogramming—across glucose, lipid, amino acid, and nucleotide pathways—remodels the tumor microenvironment to suppress anti‐tumor immunity and promote immune escape. Targeting these metabolic axes offers promising strategies to overcome immunotherapy resistance and enhance cancer treatment.
Guoqing Xiang   +5 more
wiley   +1 more source

STABILITAS STRUKTUR BAWAH BANGUNAN LEPAS PANTAI UNTUK FLOATING WIND TURBINE DENGAN SISTEM TENSION LEG-SPAR PLATFORM [PDF]

open access: yes, 2017
Floating Wind Turbine with Tension Leg – Spar Platform adalah pembangkit listrik tenaga angin yang dibangun terapung di daerah laut dengan platform gabungan Tension Leg Platform dan Spar Bouy.
Pujiharjo, Alwafi   +2 more
core   +1 more source

Multi‐Technique Integration Identifies O‐GlcNAc Transferase in Fibroblast‐Like Synoviocytes as a Therapeutic Target for Rheumatoid Arthritis

open access: yesAdvanced Science, EarlyView.
AI‑guided single‑cell transcriptomics identifies OGT as a key regulator enriched in rheumatoid arthritis fibroblast‑like synoviocytes (RA‐FLSs). Inflammatory stimuli activate the OGT–SAP130 axis, which modulates the H3K27ac/H3K27me3 balance and epigenetically silences BTG2, promoting aggressive transformation of RA‑FLSs.
Duoli Xie   +14 more
wiley   +1 more source

Investigation of motion response suppression characteristics in floating platforms equipped with novel spiral side plates

open access: yesEnergy Science & Engineering
To enhance the stability of floating wind turbine platforms, this study combines the structural characteristics of helical side plates and proposes the installation of serrated helical side plates on Spar wind turbine platforms.
Yu Jing‐mei, Bai Chun‐long
doaj   +1 more source

CAR‐Engineered Cell Therapies Beyond Cancer: Reprogramming Fibrosis and Immune‐Mediated Inflammation

open access: yesAdvanced Science, EarlyView.
CAR‐engineered cell therapies are expanding beyond cancer toward immune resetting, pathological‐cell clearance, matrix remodeling, and microenvironmental reprogramming in autoimmune, inflammatory, and fibrotic diseases. This Review compares CAR‐T, CAR‐macrophage, and CAR‐NK platforms and proposes controllable spatiotemporal reprogramming to align ...
Peng Jun Xu   +6 more
wiley   +1 more source

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