Results 81 to 90 of about 1,987,967 (281)

Design and hydrodynamic performance of 15 MW Spar-type floating offshore wind turbine platform

open access: yesZhongguo Jianchuan Yanjiu
ObjectivesA new Spar-type floating wind turbine platform design scheme is proposed for a 15 MW floating wind turbine, and its performance is analyzed. MethodsBased on potential flow theory, the frequency domain hydrodynamic calculation of the platform is
Lin LIN   +5 more
doaj   +1 more source

Selective Modulation of OTUB1 Noncanonical Function via a bioPhosTAC Strategy

open access: yesAdvanced Science, EarlyView.
This work positions the versatile performance of the peptide‐based bioPhosTAC platform for dissecting phosphorylation‐dependent biology and expanding the scope of induced‐proximity technologies. We demonstrated that selective manipulation of a tyrosine phosphorylation site is sufficient to propagate coordinated cellular consequences.
Seung Un Seo   +7 more
wiley   +1 more source

Floating Platform and Mooring Line Optimization for Wake Loss Mitigation in Offshore Wind Farms Through Wake Mixing Strategy

open access: yesEnergies
Floating offshore wind turbines present peculiar characteristics that make them particularly interesting for the implementation of wind farm control strategies such as wake mixing to increase the overall power production.
Guido Lazzerini   +2 more
doaj   +1 more source

Gut Microbiota‐Isoallolithocholic Acid Crosstalk Promotes Calcium Oxalate Kidney Stone Formation via PARP1‐Mediated Parthanatos

open access: yesAdvanced Science, EarlyView.
ABSTRACT Bile acids have been implicated in calcium oxalate (CaOx) nephrolithiasis. Here, we employ multi‐omics approaches to identify isoallolithocholic acid (isoalloLCA) as the key bile acid elevated in the feces, serum, kidney, and urine of CaOx rats, confirmed by spatial metabolomics.
Zijian Zhou   +9 more
wiley   +1 more source

Factors Affecting Dynamic Tension of Multi-Component Mooring System of Deepwater Spar Platform

open access: yesShiyou jixie, 2021
Tension of anchor chain is a key indicator for evaluating the structural performance of the mooring system. In this paper, in order to analyze the factors affecting the dynamic tension of deepwater Spar platform mooring systems, the influence of cable ...
Wu Changxu   +5 more
doaj  

A Cascaded DNA Nanocircuit for Multi‐Signal‐Responsive Precision siRNA Delivery in Cancer Therapy

open access: yesAdvanced Science, EarlyView.
A cascaded dual‐AND logic DNA nanocircuit is engineered to respond to three tumor‐specific signals in a sequential manner: extracellular acidic pH, membrane‐overexpressed nucleolin (NCL), and intracellular glutathione (GSH). This programmable system selectively releases siPARP1 in glioblastoma (GBM), effectively silencing PARP1 and reversing TMZ ...
Yan Zhao   +14 more
wiley   +1 more source

The Spar

open access: yes, 2016
Menu from The Spar restaurant in Olympia, WA. Salads, sandwiches, soups, build-a-burger basket, traditional burgers, beverages, milkshakes, specialty of the house, steaks, pasta & rice, other entrees, chicken entrees, from the sea, omelettes, breakfast ...
The Spar
core  

RESPONSES OF CLASSIC SPAR PLATFORM SUBJECTED TO REGULAR WAVES [PDF]

open access: yes, 2008
Increasing demand for Oil and Gas and decreasing onshore reserves has lead to Deep water exploration therefore it has accelerated the need to explore structures suitable for these depths, which operate more economically in deep water.
ABDALLA EL-KHALIF A, ABUBAKR ELAMIN
core  

Targeting the PHB2–ACSL3 Lipid‐Remodeling Axis Overcomes Cisplatin Resistance by Restoring Ferroptosis in Gastric Cancer

open access: yesAdvanced Science, EarlyView.
ABSTRACT Platinum‐based chemotherapy resistance remains a major obstacle in gastric cancer (GC) treatment. Through integrated transcriptomic profiling of cisplatin‐resistant xenografts and pharmacogenomic interrogation of the NCI‐60 dataset, we identified Prohibitin‐2 (PHB2) as a previously unrecognized determinant of chemoresistance.
Liang Xu   +10 more
wiley   +1 more source

A kereskedelmi márka politika bemutatása a SPAR Magyarország Kereskedelmi Kft példáján keresztül

open access: yes, 2012
Szakdolgozatom témájának a saját márkás termékeket választottam. Bemutatásához a Spar kereskedelmi lánc üzleteiben forgalmazott termékeit vizsgáltam. Mivel a Spar kereskedelmi üzletlánc dolgozója vagyok, ebből kifolyólag a dolgozatomban felhasználtam a ...
Móré, Renáta
core  

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