Results 101 to 110 of about 29,961 (262)

Secreted protein acidic and rich in cysteine (SPARC) induces epithelial-mesenchymal transition, enhancing migration and invasion, and is associated with high Gleason score in prostate cancer

open access: yesAsian Journal of Andrology, 2019
Secreted protein acidic and rich in cysteine (SPARC) is a matricellular protein highly expressed in bone tissue that acts as a chemoattractant factor promoting the arrival of prostate cancer (PCa) cells to the bone marrow.
Fernanda López-Moncada   +3 more
doaj   +1 more source

An update on the landscape of collagen bioactive fragments

open access: yesThe FEBS Journal, EarlyView.
The remodeling of the extracellular matrix releases collagen bioactive fragments, which exert molecular functions and regulate numerous biological processes via several signaling pathways. Here, we summarize the latest findings describing the roles of major bioactive fragments from collagens I, IV, VI, and XVIII in various physiological and ...
Sylvie Ricard‐Blum, Julie Fradette
wiley   +1 more source

Proteolytic remodelling of the extracellular matrix by pericytes

open access: yesThe FEBS Journal, EarlyView.
Pericytes are specialised perivascular cells intimately connected with endothelial cells and essential for the maintenance of vascular beds. They contribute to the formation and remodelling of the extracellular matrix by actively secreting proteases and protease inhibitors.
Tina Burkhard   +4 more
wiley   +1 more source

Benchmarking the SPARC software program for estimating solubilities of naphthalene and anthracene in organic solvents

open access: yes, 2011
The SPARC software program was benchmarked for calculating the solubilities of two representative polyaromatic hydrocarbons (PAHs), naphthalene and anthracene, in a range of organic solvents at various temperatures.
Sierra Rayne, Kaya Forest
core   +1 more source

Evaluating maturity of organic matter in hydrated C1 and CM‐like clasts and a dehydrated clast within a polymict eucrite and a howardite

open access: yesMeteoritics &Planetary Science, EarlyView.
Abstract Volatile‐rich xenolithic clasts in different types of brecciated meteorites represent unique pristine solar system material. This study investigates the maturity and thermal history of organic matter using Raman spectroscopy and aqueous alteration effects using infrared spectroscopy in the matrix of 15 volatile‐rich clasts (C1 and CM‐like ...
Swarna Prava Das   +7 more
wiley   +1 more source

The ‘SPARC’ of life: Analysis of the role of osteonectin/SPARC in pancreatic cancer (Review)

open access: yesInternational Journal of Oncology, 2016
Pancreatic ductal adenocarcinoma (PDAC) is one of the most clinically challenging cancers to manage. An estimated 48,960 people will be diagnosed with pancreatic cancer in 2015, of that population, 94% are projected to perish within 5 years. These dismal survival rates can be attributed, in part, to an advanced diagnosis occurring in 80% of cases.
Monica K, Rossi   +2 more
openaire   +3 more sources

Understanding exosomes in diabetic wound healing

open access: yesPeriodontology 2000, EarlyView.
Abstract Background Diabetic wounds signify a major complication of diabetes mellitus, characterized by chronic inflammation, compromised angiogenesis, and high risk of infection, amputation, and mortality. Contemporary therapies remain limited in efficacy and durability.
Paras Ahmad   +4 more
wiley   +1 more source

Report on the 1st SPARC Stratospheric Network for the Assessment of Predictability (SNAP). April 24-26 April 2013, Reading, UK

open access: yes, 2016
Stratospheric Network for the Assessment of Predictability (SNAP), 24-26 April 2013, Reading, UKThe first SPARC Stratospheric Network for the Assessment of Predictability (SPARC-SNAP) workshop was organized in the Department of Meteorology, University of
Charron, Martin   +9 more
core  

No effect of acute and chronic supramaximal exercise on circulating levels of the myokine SPARC [PDF]

open access: yes, 2017
Myokines may play a role in the health benefits of regular physical activity. Secreted protein acidic rich in cysteine (SPARC) is a pleiotropic myokine that has been shown to be released into the bloodstream by skeletal muscle in response to aerobic ...
Songsorn, Preeyaphorn   +2 more
core   +1 more source

Evolution of dental tissue mineralization: an analysis of the jawed vertebrate SPARC and SPARC-L families

open access: yesBMC Evolutionary Biology, 2018
Background The molecular bases explaining the diversity of dental tissue mineralization across gnathostomes are still poorly understood. Odontodes, such as teeth and body denticles, are serial structures that develop through deployment of a gene ...
Sébastien Enault   +6 more
doaj   +1 more source

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