Results 101 to 110 of about 22,630 (210)

Chemotherapy‐Induced Skeletal Muscle Dysfunction and Cognitive Impairment: A Muscle‐Brain Mechanistic Framework With Implications for Exercise Oncology

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 5, October 2026.
ABSTRACT Chemotherapy commonly induces skeletal muscle dysfunction and cognitive impairment, complications that reduce treatment tolerance and quality of life. Skeletal muscle mass frequently declines during chemotherapy, with cohort studies reporting losses of 3%–10% across treatment courses, while chemotherapy‐induced cognitive impairment affects up ...
SoYoung Ahn   +10 more
wiley   +1 more source

C1qc Mediates Blood–Brain Barrier Disruption in a Mouse Model of Intracerebral Haemorrhage Through Microglia‐Derived Migrasomes

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 10, October 2026.
Microglia‐derived migrasomes induce vascular endothelial pyroptosis through C1qc delivery, uncovering a novel mechanism of blood–brain barrier (BBB) disruption after intracerebral haemorrhage (ICH) and proposing a novel therapeutic strategy targeting extracellular vesicles (EVs).
Mengyuan Li   +17 more
wiley   +1 more source

Profile of SPARC

open access: yes, 2006
Heather Joseph, The Scholarly Publishing and Academic Resources Coalition: An evolving agenda, C&RL News, February 2006. Heather Joseph is the executive director of SPARC. Excerpt: Update. Also see Heather's presentation at the UBC Library / SLAIS Colloquium, University of British Columbia Library, SPARC Futures : an evolving agenda.
openaire   +1 more source

Exclusive enteral nutrition containing transforming growth factor‐β improves intestinal barrier function in a colitis mouse model

open access: yesJournal of Pediatric Gastroenterology and Nutrition, Volume 83, Issue 4, Page 692-702, October 2026.
Abstract Objectives Exclusive enteral nutrition (EEN) is the first‐line treatment for pediatric Crohn's disease, but its mechanisms of action remain poorly understood. Our aim was to identify the mechanisms that could explain the anti‐inflammatory effects of EEN, studying the nutritional composition and transforming growth factor‐β (TGF‐β) effects, in ...
Kawthar Boumessid   +6 more
wiley   +1 more source

The Proteome of Plasma Extracellular Vesicles in Latent and Active Tuberculosis Reveals Phase‐Specific Composition and Immunometabolic Insights

open access: yesFASEB BioAdvances, Volume 8, Issue 10, October 2026.
Plasma extracellular vesicles (EVs) from individuals with latent (LTB) or active tuberculosis (ATB) exhibit distinct proteomic compositions, reflecting the underlying immunometabolic states of each phase. In LTB, EVs are enriched in proteins associated with tissue remodeling and lipid metabolism, including TGFβ, APOA1, and APOE, which may participate ...
Eliud S.‐Peregrino   +13 more
wiley   +1 more source

ZNF865 (BLST) a Novel Regulator of DNA Damage and Cell Senescence in Back Pain

open access: yesAging Cell, Volume 25, Issue 10, October 2026.
ZNF865 (BLST) has previously been classified as part of the “unknome”, but here in the context of back pain, we demonstrate the first functional characterization of ZNF865. We demonstrate that it regulates genomic stability and subsequent senescence, and that downregulation in the intervertebral disc leads to pain behavior in rodent models.
Christian Lewis   +12 more
wiley   +1 more source

The histone deacetylase inhibitor, suberoylanilide hydroxamic acid, restores blood–brain barrier integrity in a human stem cell‐based model of ischaemic stroke

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 19, Page 5791-5812, October 2026.
Ischaemic stroke is characterised by acute cerebrovascular occlusion and blood–brain barrier (BBB) breakdown. Our results indicated that the histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA) ameliorated the loss of BBB integrity, changed the morphology of brain endothelial cells, increased the level of basement membrane and ...
Anikó Szecskó   +14 more
wiley   +1 more source

Landscape Mapping Reveals Depth‐Dependent Regional Heterogeneity in Soil Microbial Diversity

open access: yesDiversity and Distributions, Volume 32, Issue 10, October 2026.
ABSTRACT Aim To identify microbial hotspots and investigate the spatial distribution and assembly mechanisms of soil bacterial and archaeal communities across a coastal ecosystem, and to assess implications for biodiversity conservation and sustainable land management. Location Yellow River Delta, China (YRD, ~13,680 km2 coastal plain). Methods A total
Xiongfeng Du   +18 more
wiley   +1 more source

Immunohistochemical expression of SPARC in odontogenic keratocysts: a comparative study with other odontogenic cysts

open access: yesBMC Oral Health
Background Secreted protein acidic and rich in cysteine (SPARC) has been shown to modulate aggressive behavior in several benign and malignant tumors.
Sopee Poomsawat   +4 more
doaj   +1 more source

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