Results 91 to 100 of about 29,961 (262)

Bielefeld Academic Search Engine (BASE): an End-user Oriented Institutional Repository Search Service

, 2006
In a SPARC position paper (http://www.arl.org/sparc/IR/ir.html) published in 2002 Raym Crow defined an institutional repository as a "digital collection capturing and preserving the intellectual output of a single or multi-university community ...
Pieper, Dirk, Summann, Friedrich ; https://orcid.org/, Pieper, Dirk ; https://orcid.org/, Summann, Friedrich   +3 more
core   +1 more source

Stratospheric and tropospheric seasonality and its implications for observation requirements in numerical weather prediction

Quarterly Journal of the Royal Meteorological Society, EarlyView.
Daily time series of zonal‐mean zonal wind (m·s−1) at 10 hPa and 60° N from 1950 to 2021 from the ERA5 reanalysis. This shows huge variability in some seasons and very little in others. We provide evidence that high‐level observations, radiosonde and satellite, are more important during the extended winter season with its very large variability ...
Bruce Ingleby, Inna Polichtchouk
wiley   +1 more source

Helical reconstruction of amyloids in cryoSPARC

Acta Crystallographica Section F, EarlyView.
We present practical guidelines for helical reconstruction of amyloid filaments in cryoSPARC, benchmarked against publicly available datasets. Our analysis defines current capabilities and limitations, and outlines optimization strategies to enable high‐throughput structural studies and therapeutic discovery.Amyloid‐mediated proteotoxicity underlies ...
Jan-Hannes Schaefer, Robert T. O'Neill, Joseph P. Donnelly, Evan T. Powers, Jeffery W. Kelly, Gabriel C. Lander   +5 more
wiley   +1 more source

Chapter 4: The LOTUS regression model [PDF]

, 2019
One of the primary motivations of the LOTUS effort is to attempt to reconcile the discrepancies in ozone trend results from the wealth of literature on the subject.
Hassler, B., Kapsomenakis, J., Godin-Beekmann, Sophie, Sofieva, Viktoria, Ball, W. T., Petropavlovskikh, I., Laeng, A., Zawada, D. J., Degenstein, D. A., Sofieva, V. F., Wild, J. D., Laine, M., Vigouroux, C., Damadeo, Robert, Damadeo, R., Taylor, Michael, von Clarmann, T., Petropavlovskikh, Irina, Steinbrecht, W., Hassler, Birgit, Balis, D., Frith, S. M., Hubert, Daan, Godin-Beekmann, S., Maillard-Barras, E., Hubert, D., Roth, C. Z., Coldewey-Egbers, M., Chang, K-L., Gruzdev, A., Misios, S., Tourpali, K., Zerefos, C. S., Weber, M., Alsing, J., Eleftheratos, K.   +35 more
core   +1 more source

Targeting SPARC by lentivirus-mediated RNA interference inhibits cervical cancer cell growth and metastasis

BMC Cancer, 2012
Background Secreted protein acidic and rich in cysteine (SPARC), a calcium-binding matricellular glycoprotein, is implicated in the progressions of some cancers.
Chen Jie, Shi Dehuan, Liu Xiaoyan, Fang Shuang, Zhang Jie, Zhao Yueran   +5 more
doaj   +1 more source

AlignPCA‐2D: PCA‐reduced Euclidean vector alignment for 2D classification in cryo‐EM

Acta Crystallographica Section D, EarlyView.
We introduce AlignPCA‐2D, a PCA‐space Euclidean alignment method for rapid and interpretable 2D classification of cryo‐EM particle images. The approach preserves essential structural variability while greatly reducing computational cost, offering a lightweight alternative to existing large‐scale cryo‐EM classification pipelines.Cryogenic electron ...
E. Ramírez-Aportela, O. L. Zarrabeitia, Y. C. Fonseca, T. Ceska, S. Subramaniam, J. M. Carazo, C. O. S. Sorzano   +6 more
wiley   +1 more source

Open Education in European Libraries of Higher Education : report (October 2022) [PDF]

Le rapport de Sparc Europe présente les résultats de leur troisième enquête annuelle sur l’open éducation (OE) et ses ressources dans les bibliothèques universitaires européennes.
SPARC Europe
core  

SPARC expression is associated with hepatic injury in rodents and humans with non-alcoholic fatty liver disease

Scientific Reports, 2018
Mechanisms that control progression from simple steatosis to steato-hepatitis and fibrosis in patients with non-alcoholic fatty liver disease (NAFLD) are unknown.
Guillermo Mazzolini, Catalina Atorrasagasti, Agostina Onorato, Estanislao Peixoto, Martin Schlattjan, Jan-Peter Sowa, Svenja Sydor, Guido Gerken, Ali Canbay   +8 more
doaj   +1 more source

Adipokines in Obese Asthma: A Complex Relationship Influenced More by Sex, Weight, and Oral Steroid Treatment Than Disease Severity

Allergy, EarlyView.
Adipokine secretion from adipose tissue may be involved in obesity‐related asthma, but it is unknown how adipokine levels relate to asthma characteristics. Plasma adipokines were measured in well‐characterized lean, overweight or obese patients with mild‐to‐moderate or severe asthma.
Lars I. Andersson, Maciej Kupczyk, Barbro Dahlén, Kenji Izuhara, Mina Gaga, Nikos M. Siafakas, Alberto Papi, Bianca Beghe, Guy Joos, Klaus F. Rabe, Elisabeth H. Bel, Sebastian L. Johnston, Pascal Chanez, Mark Gjomarkaj, Peter H. Howarth, Ewa Niżankowska‐Mogilnicka, Roelinde Middelveld, Sven‐Erik Dahlén, Apostolos Bossios, Anna James, on behalf of the BIOAIR (Longitudinal Assessment of Clinical Course and BIOmarkers in Severe Chronic AIRway Disease) and ChAMP consortia   +20 more
wiley   +1 more source

The roles of secreted protein acidic and rich in cystiene (Sparc) in intestinal inflammation, healing and fibrosis

, 2012
Secreted Protein Acidic and Rich in Cysteine (SPARC) is a matricellular protein expressed during tissue repair and regulates cell proliferation and migration.
Ng, Yoke Leng
core