Results 91 to 100 of about 9,779,891 (294)

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Optimise initial spare parts inventories: an analysis and improvement of an electronic decision tool. [PDF]

Control of spare parts is very difficult as demands can be very low (once in a few years is no exception), while the consequences of a stockout can be severe.
Dekker, R., Sinnema, S.M., Trimp, M.E., Teunter, R.H.   +3 more
core  

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Improvement of spare part inventory for process machine [PDF]

วิทยานิพนธ์ (วศ.ม.)--จุฬาลงกรณ์มหาวิทยาลัย, 2554วิทยานิพนธ์มีวัตถุประสงค์เพื่อศึกษาแนวทางในการปรับปรุงระบบการจัดการอะไหล่คงคลังสำหรับเครื่องจักรการผลิตในโรงงานกรณีศึกษา ซึ่งประสบปัญหาเกี่ยวกับการมูลค่าจัดเก็บอะไหล่คงคลังสูงถึง 81 ล้านบาท ส่งผลให้แต่ละป ...
ปริญญา จันทรวินิจ
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

The first cut

, 2011
Catalogue of an exhibition held at the RMIT University Project Space/Spare Room gallery, 7-24 Mar. 2011.The First Cut is a participant of the 2011 L'Ore?al Melbourne Fashion Festival Cultural Program.Curated by Stephen Gallagher.Artists: Ricarda Bigolin,
RMIT Project Space/Spare Room
core  

Recognition of Industrial Spare Parts Using an Optimized Convolutional Neural Network Model

Information
Spare parts search and retrieval processes are of paramount importance in manufacturing and supply chains. Image recognition using 2D and 3D image properties plays an important part in the success of such processes, as it facilitates the identification ...
Chandralekha Mohan, Takfarinas Saber, Priyadharshini Jayadurga Nallathambi   +2 more
doaj   +1 more source