Results 61 to 70 of about 9,779,891 (294)

A REVERSE ENGINEERING APPROACH TO OBTAIN THE 3D MODEL OF A SPARE PART

Nonconventional Technologies Review, 2018
The current stage is characterized by the steady growth of competition between manufacturing companies, which causes diversifying the range of products and find new methods to shorten the time for the development of a new product.
Iulian Stanasel, Traian Buidos
doaj  

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Managing Dead Stock Spare Part Using House of Risk Framework [PDF]

, 2018
House of risk framework had been applied widely for identify root cause of problem in supply chain. However, house of risk framework usage to mitigate problem in spare part stocks are still limited.
Hakim, Muhammad Saiful, Baihaqi, Imam, Atmaja, Immanuel Rio   +2 more
core   +1 more source

Integrated maintenance and spare part optimization for moving assets [PDF]

, 2018
We consider an integrated maintenance and spare part optimization problem for a single critical component of a moving asset for which the degradation level is observable. Degradation is modeled as a function of the current operating mode, mostly dictated
van Houtum, GJJAN, Eruguz, Sena, Tan, T
core   +5 more sources

Spare parts stock management: Classification and policy assignment [PDF]

FME Transactions
Spare parts management is a maintenance management function that aims to support maintenance activities. It intends to provide real-time information about the available quantities for each spare part and to adopt stock management policies that assure its
Teixeira Catarina, Lopes Isabel, Figueiredo Manuel   +2 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Positioning of spare part contracts in the servitisation process [PDF]

, 2015
In today's competitive market, servitisation as a relatively new term in academia and industry is finding its place to offer services within selling products, as after sale products and sometimes offering services instead of products.
Sabaei, Davood, Roy, Rajkumar, Erkoyuncu, John   +2 more
core   +5 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Spare Part Replenishment Strategy for Electronic Product Based on Model Predictive Control

Complex System Modeling and Simulation
After-sale service plays an essential role in the electronics retail industry, where providers must supply the required repair parts to consumers during the product warranty period.
Xingchang Fu, Chu-ge Wu, Bo Fu, Yuanqing Xia   +3 more
doaj   +1 more source