Results 101 to 110 of about 158,405 (292)

Patient perspective of Hesitancies and strategies to increase cancer clinical trial participation

open access: yesJournal of Clinical and Translational Science
Introduction: Strategies to improve accrual and reduce barriers to cancer clinical trials participation are critical for the advancement and implementation of new treatments and processes to improve cancer patient outcomes.
Bre-Anne Fifield   +14 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Aeronautic Spark Plugs

open access: yes
This mounted collection of aeronautic spark plugs illustrates one phase of the extensive program on ignition apparatuses at the National Bureau of Standards (NBS) which was sponsored by the National Advisory Committee for Aeronautics (NACA) from 1917 to ...
Bleininger, Albert V.; Campion Spark Plug (Company); Frenchtown Porcelain Company
core  

SPARK SUPPRESSION [PDF]

open access: yesJournal of the Experimental Analysis of Behavior, 1958
J, Norris, R, Kelleher
openaire   +2 more sources

The Spark, Volume 5, No. 13

open access: yes, 1981
TIie lparll A Central Piedmont Community College Student Publication Taylor Hall 102 Charlotte, North Carolina Volume 5 Number 13 Friday, May 29, 1981 (704) 373-6751 , 373-6665 Stampede Western Day (and night) byBre nd0 !:::::end Louann draws a herd of ...
Spark Staff
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

The Spark, Volume 7, No. 6

open access: yes, 1983
This issue celebrates the 20th anniversary of Central Piedmont. It also focuses on the June 1983 Dental Hygiene graduates, instructor Joe Bathanti winning a statewide contest, Jesse Jackson inspiring Central Piedmont students to vote, the creation of the
Spark Staff
core  

AAV vectors trigger DNA damage response-dependent pro-inflammatory signalling in human iPSC-derived CNS models and mouse brain

open access: yesNature Communications
Adeno-associated viral (AAV) vector-based gene therapy is gaining foothold as treatment for genetic neurological diseases with encouraging clinical results.
Helena Costa-Verdera   +22 more
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

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