Results 121 to 130 of about 158,405 (292)
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
, 1981 Tllel11arll Central P1eclmont Community College Charlotte, North Carolina Taylor Hall 102 Friday, September 14, 1981 (704) 373-6665 Vol. 5, No. 16 Summer Theatre- A Success CAMELOT June 25-July 11 THE .MOUSETRAP July 15-25 OKLAHOMA!
Spark Staff
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, 1982 c:: "E' :: 0 cc --0 u en > .c .s 0 ..c:: C. . !!: C. .."c:': u .>c -0 0 ..c:: C. Fi l -e,, TIie lpark CENTRAL PIEDMONT COMMUNITY COLLEGE Taylor Hall 102 Charlotte, North Carolina Maydaze proved to be full of relaxation ~nd enjoyment.
Spark Staff
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FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
, 1984 Taylor Hall 102 373-6665 A STUDENT NEWS PUBLICATION VOL. 12, NO. 3 P.O. Box 35009, Charlotte, N.C. 28235 December 7, 1984 - S ecial . :O TIie lpark ~ pc:;f:lecttO ?ft clppr Jssue 0/Jd, ~ CENTRAL PIEDMONT c1J-s - - COMMUNITY COLLEGE ·--- SGA ELECTIONS ...
Spark Staff
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Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
, 1978 Tll• lparll PUBLISHED BY AND FOR THE OVER 25,000 STUDENTS OF CENTRAL PIEDMONT COMMUNITY COLLEGE Volume 3 Wednesday, October 4, 1978 Number 1 REGISTER TO VOTE ON CAMPUS TODAY States First Alumni Chapter Installed Phi Theta Kappa Hosts Regional Leadership ...
Spark Staff
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