Implementing the screening for poverty and related social determinants and intervening to improve knowledge of and links to resources (SPARK) in primary care clinics across Canada. [PDF]
Kosowan L +20 more
europepmc +1 more source
The Effect of Spark Timing on the Spark Ignition
In this work the effect of spark timing on the spark ignition engines is investigated by computer simulation and experimental test for speeds of (1500,2000,2500,3000 and 3500)rpm at spark timing of (20o,30o,40o,50o and 60o) before TDC for each speed.
openaire +1 more source
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Decoding Structure-Property Relationships in Anion Exchange Membranes via a Chemically Informed Dual-Channel Graph Attention Network. [PDF]
Chen W +6 more
europepmc +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Preparation and Parameter Optimization of Nanoscale Magnesium Hydroxide Colloids by the Electrical Spark Discharge Method under Ambient Conditions. [PDF]
Chung MY +4 more
europepmc +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
In-situ magnetic field-controlled synthesis of SnO<sub>2</sub>-SnO nanoparticle films for enhanced photovoltaic self-cleaning and anti-soiling. [PDF]
Jhuntama N +4 more
europepmc +1 more source
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Effects of the SPARK program on motor skills, physical fitness, and social skills in children and adolescents: a systematic review. [PDF]
Peng L +5 more
europepmc +1 more source

