Results 151 to 160 of about 158,405 (292)
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
, 1991 Dr. Ruth Shaw provides updates regarding the budget at the quarterly Student Forum, urging students to write to their state legislators. Opinion articles focus on the Gulf War, patriotism, and what comes next after the war.
Spark Staff
core
PARAFAC-SPARK: Parallel tensor decompositions on spark
, 2019 Tensors are higher order matrices, widely used in many data science applications and scienti c disciplines. The Canonical Polyadic Decomposition (also known as CPD/PARAFAC) is a widely adopted tensor factorization to discover and extract latent features of tensors usually applied via alternating squares (ALS) method.
openaire +2 more sources
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
, 1978 TIie lparll-~:~- PUBLISHED BY AND FOR THE OVER 25,000 STUDENTS OF CENTRAL PIEDMONT CO~UNITY COLLEGE Volume 3 Wednesday, November 15, 1978 Number 5 CPCC BONDS PASS This calendar of events includes items of general interest on campus, at other ...
Spark Staff
core
Evaluating the performance of DeepSeek-V3, Doubao, ERNIE 4.5 Turbo and iFLYTEK Spark in the Chinese national nursing licensing examination: a cross-sectional comparative study. [PDF]
Front Artif IntellYang M, Zhu L, Zhang Z, Xu Q.
europepmc +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Measuring PINK1 Activity in Single Cells Using a PINK1 Kinase Activity Reporter. [PDF]
Bio ProtocVineall KG, Schmitt DL.
europepmc +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source