Results 151 to 160 of about 504,110 (280)

The Silent Pandemic: Preventing Non-communicable Diseases from Taking Over the Arabian Gulf

Oman Medical Journal
Wesley Kuijpers
doaj   +1 more source

Visualizing PINK1 Activity Dynamics in Single Cells with a Phase Separation-Based Kinase Activity Reporter. [PDF]

ACS Sens
Vineall KG, Andrikopoulos A, Sun MJ, Yan A, Hartanto ER, Schmitt DL.   +5 more
europepmc   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Optimisation of the WC-Co Composite Manufacturing Process Using Spark Plasma Sintering Technology with the DOE Methodology. [PDF]

Materials (Basel)
Kruzel R, Dembiczak T, Bałaga Z, Lis M, Kołacz D, Wachowicz J, Kuśmierczak S, Náprstková N.   +7 more
europepmc   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Nitrogen fixation in a non-equilibrium spatially distributed electric field. [PDF]

Nat Commun
Guo S, Wang Y, Guo Y, Goldsmith BR, Zhao H.   +4 more
europepmc   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Data Sharing and Global Public Health: Defining What We Mean by Data

Frontiers in Digital Health, 2020
Nina Schwalbe, Nina Schwalbe, Nina Schwalbe, Brian Wahl, Brian Wahl, Jingyi Song, Susanna Lehtimaki   +6 more
doaj   +1 more source

Primary care provider and clinic staff perspectives on the collection of demographic and social needs data in primary care clinics across five Canadian provinces. [PDF]

Fam Med Community Health
Gupta A, O'Rourke JJ, Kosowan L, Howse D, Williams L, Adekoya I, Seshie AZ, Delahunty-Pike A, Smithman MA, Abaga E, Zsager A, Robinson M, Marshall EG, Aubrey-Bassler K, Neudorf C, Muhajarine N, Fortuna I, Pinto AD.   +17 more
europepmc   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source