Results 71 to 80 of about 504,110 (280)

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana, Mariana Maschietto, Daniela Paz Leal, Ricardo de Santos de Oliveira, Mayara Ferreira Euzébio, Antonio Carlos dos Santos, Luciano Neder, Carlos Alberto Scrideli, Elvis Terci Valera   +8 more
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

AI can outperform humans in predicting correlations between personality items

Communications Psychology
We assess the abilities of both specialized deep neural networks, such as PersonalityMap, and general LLMs, including GPT-4o and Claude 3 Opus, in understanding human personality by predicting correlations between personality questionnaire items.
Philipp Schoenegger, Spencer Greenberg, Alexander Grishin, Joshua Lewis, Lucius Caviola   +4 more
doaj   +1 more source

Prioritization approaches in the development of health practice guidelines: a systematic review

BMC Health Services Research, 2019
Background Given the considerable efforts and resources required to develop practice guidelines, developers need to prioritize what topics and questions to address.
Amena El-Harakeh, Rami Z. Morsi, Racha Fadlallah, Lama Bou-Karroum, Tamara Lotfi, Elie A. Akl   +5 more
doaj   +1 more source

Measurement of spark probability of GEM detector for CBM muon chamber (MUCH)

, 2015
The stability of triple GEM detector setups in an environment of high energetic showers is studied. To this end the spark probability in a shower environment is compared to the spark probability in a pion beam.Comment: 5 pages, 10 ...
Abuhoza, A., Biswas, S., Frankenfeld, U., Garabatos, C., Hehner, J., Kleipa, V., Morhardt, T., Schmidt, C. J., Schmidt, H. R., Wiechula, J.   +9 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Combustion characteristics in the transition region of liquid fuel sprays [PDF]

A number of important effects have been observed in the droplet size transition region in spray combustion systems. In this region, where the mechanism of flame propagation is transformed from diffusive to premixed dominated combustion, the following ...
Cernansky, N. P., Namer, I., Tidona, R. J.   +2 more
core   +1 more source

Advances in the Development of Micropattern Gaseous Detectors with Resistive Electrodes

, 2010
We describe the most recent efforts made by various groups in implementing resistive electrodes in micropattern gaseous detectors with the aim to combine in the same design the best features of RPCs (for the example, their robustness and spark protection
Agocs, Akimoto, Bidault, Bondar, E. Nappi, F. Pietropaolo, Fonte, Fonte, P. Fonte, P. Martinengo, P. Picchi, Periale, R. Oliveira, Santonico, Santonico, V. Peskov, Van der Graaf   +16 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source