Results 71 to 80 of about 55,467 (261)

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

An Overview of Silica Scaling Reduction Technologies in the Geothermal Market

open access: yesEnergies
Renewable energy sources play a vital role in the energy mix with geothermal energy providing an opportunity to harness the natural heat coming from the Earth for sustainable power production.
Rochelle Longval   +3 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Measuring electrophysiological changes induced by sub-concussive impacts due to soccer ball heading

open access: yesFrontiers in Neurology
A growing body of research suggests that impacts to the head, including sub-concussive impacts, carry risks for long-term detrimental effects on cognition and brain health.
Geoffrey Brookshire   +16 more
doaj   +1 more source

Acoustic spark chamber

open access: yesNuclear Instruments and Methods, 1962
Abstract Positions of the tracks produced by cosmic rays in a 15-kV four gap spark chamber were determined by measuring the time of flight T of the shock waves produced by sparks in argon. A pair of acoustic probes, using barium-titanate piezoelectric transducers is placed in each gap of the spark chamber. Times, T 1 i, in >sec for each probe i ,
Maglić, Bogdan C, Kirsten, Frederick A
openaire   +4 more sources

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Modeling of Tensile Stress Distribution Considering Anisotropy of Mechanical Properties of Thin-Walled AlSi10Mg Samples Obtained by Selective Laser Melting

open access: yesJournal of Manufacturing and Materials Processing
The work that is being presented demonstrates that there is a critical point at which the engineering stress–strain diagram’s elastic–plastic region transitions to yield and fracture stresses.
Sergey N. Grigoriev   +8 more
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

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