Results 41 to 50 of about 410,473 (378)

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

A PIV-Guided Large-Eddy Simulation of In-Cylinder Flows

Oil & Gas Science and Technology, 2017
A combination of Large-Eddy Simulation (LES) and Particle Image Velocimetry (PIV) was utilized to investigate the three-dimensional in-cylinder flow within an optically accessible Direct Injection Spark Ignition (DISI) engine at motored engine operation.
Nicollet Franck, Krüger Christian, Schorr Jürgen, Nicoud Edouard, Colin Olivier, Angelberger Christian, Bode Johannes, Böhm Benjamin   +7 more
doaj   +1 more source

Methodological Design Optimization of a Marine LNG Internal Combustion Gas Engine to Burn Alternative Fuels

Journal of Marine Science and Engineering, 2023
Marine emission policies are becoming more demanding; thus, ship propulsion and power generation technologies need to be adapted to current scenarios. LNG is already considered to be a transition fuel, and new alternative marine fuels are emerging.
Ander Ruiz Zardoya, Iñigo Oregui Bengoetxea, Angel Lopez Martinez, Iñaki Loroño Lucena, José A. Orosa   +4 more
doaj   +1 more source

Tachometer Based Mikrokontroller Atmega16 With Electromagnetic Induction Method On Spark Plug Wires As Ancillary Equipment Service Light On Motorcycle [PDF]

, 2013
The final project was created with the aim of building the hardware, software, and know the performance of the Tachometer Based Mikrokontroller Atmega16 By Electromagnetic induction Method In spark plug Wires As Ancillary Service Light Fixtures on the ...
Abid Kamal, Luthfi
core  

Characterization of a spark ignition system for flameholding cavities [PDF]

, 2014
This paper presents an experimental investigation of a capacitive-discharge spark ignition system designed to promote ignition in CH- and CH-fuelled supersonic combustors.
Brieschenk S., Calcote H. F., Chao J., Jacobsen L. S., Kim H. J., Maurice L. Q., McBride B. J., Murthy S. N. B., Pergament H. S., A, Shapiro A. H., Stalker R. J.   +10 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Aspects of experimental investigations of laser plug ignition use at spark ignition engine

MATEC Web of Conferences, 2017
Nowadays, the necessity of pollutant emissions reduction brings to the fore new technologies developed for a better control of the combustion process. Ignition is the process of starting radical reactions until a selfsustaining flame has developed and ...
Done Bogdan
doaj   +1 more source

Characterisation of Flame Development with Hydrous and Anhydrous Ethanol Fuels in a Spark-Ignition Engine with Direct Injection and Port Injection Systems [PDF]

, 2014
This paper presents a study of the combustion mechanism of hydrous and anhydrous ethanol in comparison to iso-octane and gasoline fuels in a single-cylinder spark-ignition research engine operated at 1000 rpm with 0.5 bar intake plenum pressure.
Aleiferis, PG, Augoye, AK
core   +1 more source

New Design of Copper–Inconel 601 Ground Electrode Spark Plug Based on a Thermo-Mechanical Model

Energies, 2020
Inconel 601 is one material of choice for intermediate- to high-temperature protective coatings for spark plugs’ ground electrodes. Production of ground electrodes of spark plugs implies the following operations: the tamping of the copper core in an ...
C. Tahri, H. Klocker, B. Beaugiraud, Christophe Bertoni, E. Feulvarch, J. Bergheau   +5 more
semanticscholar   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source