Results 171 to 180 of about 167,687,783 (193)

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

A study of X-ray emission from laboratory sparks in air at atmospheric pressure

Journal of Geophysical Research D: Atmospheres, 2008
Dwyer, Joseph   +2 more
exaly  

Lifecycle of laser-produced air sparks

Physics of Plasmas, 2015
Mark Phillips   +2 more
exaly  

Hypersensitivity of BKCa to Ca2+ Sparks Underlies Hyporeactivity of Arterial Smooth Muscle in Shock

Circulation Research, 2007
Guiling Zhao, Ke-Seng Zhao, Cheng Heping
exaly  

X rays from 80-cm long sparks in air

Geophysical Research Letters, 2008
Vernon Cooray   +2 more
exaly  

Ca2+ sparks promote myogenic tone in retinal arterioles

British Journal of Pharmacology, 2013
Charles Norman Scholfield   +2 more
exaly  

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