Results 191 to 200 of about 15,041 (261)

From prediction to intervention: Paradigm shifts in causal AI for precision medicine and large‐scale cohorts

open access: yesVIEW, EarlyView.
Large‐scale cohorts and multimodal biomedical data have enabled powerful predictive models for clinical risk stratification, but prediction alone cannot guide effective interventions. This review introduces causal artificial intelligence as a design‐first framework that integrates target trial emulation, causal discovery, and robust effect estimation ...
Linlin Cao   +5 more
wiley   +1 more source

Gut microbiota dysbiosis and Long COVID susceptibility in chronic kidney disease

open access: yesVIEW, EarlyView.
This study investigated gut microbiota dysbiosis and its association with Long COVID susceptibility in 224 hemodialysis patients. We found that 35.3% of patients developed Long COVID, characterized by neurological symptoms and elevated inflammatory markers, accompanied by significant gut microbiota alterations including enriched proinflammatory taxa ...
Meiling Jin   +5 more
wiley   +1 more source

Plasma insulin‐like growth‐factor 1 (IGF‐1) concentrations predict early life‐history traits in a wild mammal

open access: yesFunctional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract The hormone insulin‐like growth factor 1 (IGF‐1) is a key player in the insulin/IGF signalling (IIS) pathway. Extensive biogerontological research demonstrates that this evolutionarily conserved nutrient‐sensing pathway plays a causal role in the regulation of growth ...
Sanjana Ravindran   +7 more
wiley   +1 more source

There Is no First Phase of the Jespersen Cycle1

open access: yesTransactions of the Philological Society, EarlyView.
Abstract This paper challenges the traditional conception of the Jespersen Cycle by arguing that no ‘pure’ first phase of the cycle exists where a single negator operates without reinforcement. Drawing on historical data from Northern Italian dialects (Piedmontese, Lombard, Emilian), we demonstrate that emphatic negative structures systematically co ...
Tommaso Mattiuzzi, Cecilia Poletto
wiley   +1 more source

GN-SCCA: GraphNet based Sparse Canonical Correlation Analysis for Brain Imaging Genetics. [PDF]

open access: yesBrain Inform Health (2015), 2015
Du L   +8 more
europepmc   +1 more source

Edges as ecological filters: Asymmetrical orientation‐specific arthropod activity across forest boundaries

open access: yesInsect Science, EarlyView.
Moderate retention forestry creates structurally sharp forest edges that act as ecological filters, shaping orientation‐specific activity of ground‐dwelling arthropods. Using drift‐fence pitfall traps, we show that activity aligned with ecotones is more frequent than activity across forest–clearcut boundaries, particularly among detritivores.
Dominik Stočes   +3 more
wiley   +1 more source

Beyond Sexual Selection: Natural Selection Related Camouflage and Thermoregulation Shape Sexual Color Dimorphism in Diploderma Lizards

open access: yesIntegrative Zoology, EarlyView.
Integrating comparative spectrometry, image analysis, and thermal modeling, we reveal that (1) females optimize crypsis via background matching, (2) males prioritize high‐contrast disruptive patterning at a significant thermoregulatory cost (reduced solar heat gain), and (3) habitat‐specific monomorphism in Diploderma slowinskii underscores ecological ...
Yuning Cao, Lin Shi, Yin Qi
wiley   +1 more source

Refining the Vertebrate Mitochondrial 12S rRNA Secondary Structure by Comparative Analysis

open access: yesIntegrative Zoology, EarlyView.
This flowchart outlines the comprehensive workflow of the study, integrating diverse bioinformatics tools (e.g., NCBI2GO, SSU‐align, bpRNA) and their sequential interactions. Key steps, such as data preprocessing, structural prediction, and evolutionary analysis, are depicted with their respective outputs (e.g., standardized records, consensus ...
Fengxia Li   +6 more
wiley   +1 more source

Productivity and Human Disturbance Shape Contrasting Distribution Patterns of Core and Occasional Bird Species in a Subtropical Forest Reserve in Southern China

open access: yesIntegrative Zoology, EarlyView.
Bird diversity hot spots in a recovering subtropical forest do not align with protected area zoning, instead occurring in experimental zones with low‐intensity human activity. This mismatch is driven by contrasting responses: Abundant core species are supported by productivity, while many species of low frequency are attracted to the habitat ...
Qing Quan   +5 more
wiley   +1 more source

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