Results 201 to 210 of about 15,041 (261)

How FDI reshapes host markets’ trade profile and politics

American Journal of Political Science, EarlyView.
Abstract A fast‐growing literature indicates that firms’ engagement in foreign direct investment (FDI) and trade is key to understanding deepening global value chains and their political implications. However, existing studies have mainly focused on the ramifications for FDI home countries while often overlooking the firm‐product level interactions ...
In Song Kim, Steven Liao, Sayumi Miyano
wiley   +1 more source

The public agglomeration effect: Urban–rural divisions in government efficiency and political preferences

American Journal of Political Science, EarlyView.
Abstract Why and when do cities vote for the left? The emergence of the urban–rural divide in the United States in the 1930s is inconsistent with canonical theories of cleavages. This paper introduces an explanation: agglomeration effects. The provision of government services is more efficient in urban environments because of nonrivalries, economies of
Theo Serlin
wiley   +1 more source

Regularized reduced rank regression for mixed predictor and response variables

British Journal of Mathematical and Statistical Psychology, EarlyView.
Abstract In this paper, we introduce the Generalized Mixed Regularized Reduced Rank Regression model (GMR4), an extension of the GMR3 model designed to improve performance in high‐dimensional settings. GMR3 is a regression method for a mix of numeric, binary and ordinal response variables, while also allowing for mixed‐type predictors through optimal ...
Lorenza Cotugno, Mark de Rooij, Roberta Siciliano   +2 more
wiley   +1 more source

The Early Upper Palaeolithic open‐air site of Friedrichsdorf‐Seulberg, Germany, in the context of the northern central European Aurignacian

Boreas, EarlyView.
Our knowledge of the Early Upper Palaeolithic occupation in northern central Europe is very limited, and recent research at the open‐air site of Friedrichsdorf‐Seulberg in Hesse, Germany, provides important new information on the Aurignacian. The site is rather small (26.5 m2) and spatial analysis identified a central hearth with two associated ...
Tilman Böckenförde, Gabriele Russo, Neda Rahimzadeh, Felix Bittmann, Nikolitsa Nikolakopoulou, Thomas Terberger   +5 more
wiley   +1 more source

Fusing functional signals by sparse canonical correlation analysis improves network reproducibility. [PDF]

Med Image Comput Comput Assist Interv, 2013
Duda JT, Detre JA, Kim J, Gee JC, Avants BB.   +4 more
europepmc   +1 more source

Increased expression of inflammasome signaling genes and proteins in selective brain regions in the intermediate stage of Alzheimer's disease

Brain Pathology, EarlyView.
Neuritic plaques increase in the intermediate stage of Alzheimer's neuropathological change. The intermediate stage of Alzheimer's disease was investigated by transcriptomics and immunohistochemistry. This revealed that inflammasome sensors NLRP1, NLRP3, and AIM2 oligomerize with ASC speck to form the inflammasome complex and initiate the downstream ...
Juan Pablo de Rivero Vaccari, David A. Davis, Andrew P. Sawaya, Susanna P. Garamszegi, Xiaoyan Sun, Ayled Barreda, Helen M. Bramlett, Sakir Humayun Gultekin, W. Dalton Dietrich, Robert W. Keane, Regina T. Vontell   +10 more
wiley   +1 more source

Distinctly altered TRPC3 and TRPC6 expression patterns in human Alzheimer's disease cortex and hippocampus

Brain Pathology, EarlyView.
Divergent remodeling of TRPC channels occurs in Alzheimer's disease, with TRPC3 increased in neurons and reactive astrocytes and TRPC6 reduced in pyramidal neurons. These alterations may contribute to calcium dysregulation, neuroinflammation, and synaptic dysfunction during AD progression.
Xingyong Chen, Zhengjun Wang, Jiaxing Wang, Dehui Kong, Xusheng Wang, Lu Lu, Peter T. Nelson, Fu‐Ming Zhou, Francesca‐Fang Liao   +8 more
wiley   +1 more source

Haemostatic changes and bleeding with anti‐IL‐6 directed therapy in autoimmune diseases

British Journal of Pharmacology, EarlyView.
Abstract Anti‐IL‐6 directed therapy, especially tocilizumab (TCZ), is widely used for the treatment of autoimmune diseases such as rheumatoid arthritis, giant cell arteritis and systemic juvenile idiopathic arthritis. Next to being a master regulator of inflammation, IL‐6 also is an important regulator of haemostasis. Although generally well tolerated,
Charlotte D. C. C. van der Heijden, Loes C. Oskam, Lenny van Bon, Chantal P. Rovers   +3 more
wiley   +1 more source

circMAN1A2 as an Isoform‐Resolved Circular RNA Hub in Cancer

Cancer Science, EarlyView.
circMAN1A2 as an isoform‐resolved circular RNA hub in cancer. circMAN1A2 is generated by back‐splicing of MAN1A2 pre‐mRNA, with alternative circularization producing multiple isoforms, including the predominant circMAN1A2(2–5). Its mechanistic interfaces include miRNA‐associated regulation, RBP binding/proteostasis control, BSJ‐mediated RNA–RNA pairing,
Hanyu Shang, Hui Wang, Yonghang Xu, Lingyun Geng, Yanqing Wang   +4 more
wiley   +1 more source

Sparse Multivariate Analysis Reveals Dissociable White Matter Networks for Cognitive and Motor Processing Speed. [PDF]

Brain Sci
Yasir S, Fidele N, Martinez-Montes E, Galan-Garcia L, Luo C, Bringas Vega ML, Valdes-Sosa PA.   +6 more
europepmc   +1 more source