Results 71 to 80 of about 15,041 (261)

Which biomarkers reveal neonatal sepsis? [PDF]

open access: yesPLoS ONE, 2013
We address the identification of optimal biomarkers for the rapid diagnosis of neonatal sepsis. We employ both canonical correlation analysis (CCA) and sparse support vector machine (SSVM) classifiers to select the best subset of biomarkers from a large ...
Kun Wang   +7 more
doaj   +1 more source

A Tutorial on Canonical Correlation Methods [PDF]

open access: yes, 2017
Canonical correlation analysis is a family of multivariate statistical methods for the analysis of paired sets of variables. Since its proposition, canonical correlation analysis has, for instance, been extended to extract relations between two sets of ...
João M. Monteiro   +17 more
core   +1 more source

Super‐Resolution Ultrasound Based Cell Tracking With Polymeric Nanobubbles

open access: yesAdvanced Materials, EarlyView.
This study presents a super‐resolution ultrasound platform for tracking cells in vivo. Biocompatible polymeric nanobubbles are used as highly echogenic intracellular labels. Following the injection of cells and microbubbles, ultrasound localization microscopy (ULM) can dynamically match the microvascular architecture and individual cell trajectories ...
Junlin Chen   +19 more
wiley   +1 more source

Sparse canonical correlation analysis applied to fMRI and genetic data fusion [PDF]

open access: yes2010 IEEE International Conference on Bioinformatics and Biomedicine (BIBM), 2010
Fusion of functional magnetic resonance imaging (fMRI) and genetic information is becoming increasingly important in biomarker discovery. These studies can contain vastly different types of information occupying different measurement spaces and in order to draw significant inferences and make meaningful predictions about genetic influence on brain ...
David Boutte, Jingyu Liu 0001
openaire   +2 more sources

Dissecting the Ecological Structure of Health and Disease in the Global Gut Microbiome

open access: yesAdvanced Science, EarlyView.
We introduce Wiredancer, a framework that identifies three continuous ecological factors of the gut microbiota. These factors exhibit distinct patterns across health and disease, jointly capturing disrupted ecological stability and offering a new perspective for precision diagnostics and therapeutic strategies.
Baoyuan Zhu   +19 more
wiley   +1 more source

Performing Sparse Regularization and Dimension Reduction Simultaneously in Multimodal Data Fusion

open access: yesFrontiers in Neuroscience, 2019
Collecting multiple modalities of neuroimaging data on the same subject is increasingly becoming the norm in clinical practice and research. Fusing multiple modalities to find related patterns is a challenge in neuroimaging analysis.
Zhengshi Yang   +539 more
doaj   +1 more source

Linking language features to clinical symptoms and multimodal imaging in individuals at clinical high risk for psychosis

open access: yesEuropean Psychiatry, 2020
Background.Abnormalities in the semantic and syntactic organization of speech have been reported in individuals at clinical high-risk (CHR) for psychosis.
S. S. Haas   +7 more
doaj   +1 more source

A Novel Longitudinal Phenotype–Genotype Association Study Based on Deep Feature Extraction and Hypergraph Models for Alzheimer’s Disease

open access: yesBiomolecules, 2023
Traditional image genetics primarily uses linear models to investigate the relationship between brain image data and genetic data for Alzheimer’s disease (AD) and does not take into account the dynamic changes in brain phenotype and connectivity data ...
Wei Kong   +6 more
doaj   +1 more source

Spatial correlation analysis using canonical correlation decomposition for sparse sonar array processing [PDF]

open access: yes, 2020
-This paper uses the canonical correlation decomposition (CCD) framework to investigate the spatial correlation of sources captured using two spatially separated sensor arrays.
Neil Wachowski   +3 more
core  

A Keratinocyte‐Mast Cell NF‐κB2/CXCL2/IL‐6 Amplification Loop Enhances Cutaneous Antifungal Defense Against C. albicans

open access: yesAdvanced Science, EarlyView.
ABSTRACT Mast cells (MCs), key innate immune sentinels at the host–environment interface, serve as primary responders to invading pathogens. However, their specific contribution to host defense against cutaneous Candida albicans (C. albicans) infection and their synergy with other immune and non‐immune cells remain poorly understood. Here, we show that
Yan Yuan   +12 more
wiley   +1 more source

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