Results 61 to 70 of about 927,730 (287)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Fast Sparse Coding for Range Data Denoising with Sparse Ridges Constraint

open access: yesSensors, 2018
Light detection and ranging (LiDAR) sensors have been widely deployed on intelligent systems such as unmanned ground vehicles (UGVs) and unmanned aerial vehicles (UAVs) to perform localization, obstacle detection, and navigation tasks.
Zhi Gao   +5 more
doaj   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Audio Source Separation Using Sparse Representations [PDF]

open access: yes, 2010
This is the author's final version of the article, first published as A. Nesbit, M. G. Jafari, E. Vincent and M. D. Plumbley. Audio Source Separation Using Sparse Representations. In W.
Nesbit, Andrew   +7 more
core   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

Learning incoherent dictionaries for sparse approximation using iterative projections and rotations [PDF]

open access: yes, 2013
This work was supported by the Queen Mary University of London School Studentship, the EU FET-Open project FP7- ICT-225913-SMALL. Sparse Models, Algorithms and Learning for Large-scale data and a Leadership Fellowship from the UK Engineering and ...
Plumbley, Mark, Barchiesi, Daniele
core   +3 more sources

Iterative thresholding for sparse approximations [PDF]

open access: yes, 2008
Sparse signal expansions represent or approximate a signal using a small number of elements from a large collection of elementary waveforms. Finding the optimal sparse expansion is known to be NP hard in general and non-optimal strategies such as ...
Blumensath, T.   +3 more
core   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

open access: yesFEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey   +4 more
wiley   +1 more source

Variational Sparse Coding [PDF]

open access: yes, 2019
Unsupervised discovery of interpretable features and controllable generation with highdimensional data are currently major challenges in machine learning, with applications\ud in data visualisation, clustering and artificial\ud data synthesis. We propose a model based\ud on variational auto-encoders (VAEs) in which\ud interpretation is induced through ...
Tonolini, Francesco   +2 more
openaire   +1 more source

Sparse and shift-invariant representations of music

open access: yes, 2006
Redundancy reduction has been proposed as the main computational process in the primary sensory pathways in the mammalian brain. This idea has led to the development of sparse coding techniques, which are exploited in this article to extract salient ...
Mike Davies   +3 more
core   +1 more source

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