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Lung cancer lesion detection in histopathology images using graph‐based sparse PCA network [PDF]

open access: yesNeoplasia: An International Journal for Oncology Research, 2023
Early detection of lung cancer is critical for improvement of patient survival. To address the clinical need for efficacious treatments, genetically engineered mouse models (GEMM) have become integral in identifying and evaluating the molecular ...
Sundaresh Ram   +11 more
doaj   +4 more sources

Dynamic Meta-data Network Sparse PCA for Cancer Subtype Biomarker Screening [PDF]

open access: yesFrontiers in Genetics, 2022
Previous research shows that each type of cancer can be divided into multiple subtypes, which is one of the key reasons that make cancer difficult to cure.
Rui Miao   +10 more
doaj   +4 more sources

A Guide for Sparse PCA: Model Comparison and Applications [PDF]

open access: yesPsychometrika, 2021
PCA is a popular tool for exploring and summarizing multivariate data, especially those consisting of many variables. PCA, however, is often not simple to interpret, as the components are a linear combination of the variables. To address this issue, numerous methods have been proposed to sparsify the nonzero coefficients in the components, including ...
Rosember Guerra-Urzola   +2 more
exaly   +7 more sources

Predicting DDI-induced pregnancy and neonatal ADRs using sparse PCA and stacking ensemble approach [PDF]

open access: yesJournal of Integrative Bioinformatics
Predicting Drug-Drug interaction (DDI)-induced adverse drug reactions (ADRs) using computational methods is challenging due to the availability of limited data samples, data sparsity, and high dimensionality.
Chaurasia Anushka, Kumar Deepak, Yogita
doaj   +2 more sources

MINIMAX BOUNDS FOR SPARSE PCA WITH NOISY HIGH-DIMENSIONAL DATA. [PDF]

open access: yesAnn Stat, 2013
We study the problem of estimating the leading eigenvectors of a high-dimensional population covariance matrix based on independent Gaussian observations.
Birnbaum A   +3 more
europepmc   +6 more sources

Visual Object Tracking Using Structured Sparse PCA-Based Appearance Representation and Online Learning [PDF]

open access: yesSensors, 2018
Visual object tracking is a fundamental research area in the field of computer vision and pattern recognition because it can be utilized by various intelligent systems.
Gang-Joon Yoon   +2 more
doaj   +2 more sources

AWGE-ESPCA: An edge sparse PCA model based on adaptive noise elimination regularization and weighted gene network for Hermetia illucens genomic data analysis. [PDF]

open access: yesPLoS Computational Biology
Hermetia illucens is an important insect resource. Studies have shown that exploring the effects of Cu2+-stressed on the growth and development of the Hermetia illucens genome holds significant scientific importance.
Rui Miao   +4 more
doaj   +2 more sources

randPedPCA: rapid approximation of principal components from large pedigrees [PDF]

open access: yesGenetics Selection Evolution
Background Pedigrees continue to be extremely important in agriculture and conservation genetics, with the pedigrees of modern breeding programmes easily comprising millions of records.
Hanbin Lee   +3 more
doaj   +2 more sources

SuSiE PCA: A scalable Bayesian variable selection technique for principal component analysis

open access: yesiScience, 2023
Summary: Latent factor models, like principal component analysis (PCA), provide a statistical framework to infer low-rank representation in various biological contexts. However, feature selection is challenging when this low-rank structure manifests from
Dong Yuan, Nicholas Mancuso
doaj   +1 more source

Hyperspectral Image Denoising via Nonlocal Spectral Sparse Subspace Representation

open access: yesIEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing, 2023
Hyperspectral image (HSI) denoising based on nonlocal subspace representation has attracted a lot of attention recently. However, most of the existing works mainly focus on refining the representation coefficient images (RCIs) using certain nonlocal ...
Hailin Wang   +5 more
doaj   +1 more source

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