Results 41 to 50 of about 72,581 (258)
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
MIMO High Frequency Surface Wave Radar Using Sparse Frequency FMCW Signals
International Journal of Antennas and Propagation, 2017 The heavily congested radio frequency environment severely limits the signal bandwidth of the high frequency surface wave radar (HFSWR). Based on the concept of multiple-input multiple-output (MIMO) radar, we propose a MIMO sparse frequency HFSWR system ...
Mengguan Pan, Baixiao Chen
doaj +1 more source
Quantization in Compressive Sensing: A Signal Processing Approach
IEEE Access, 2020 The influence of finite-length registers and the corresponding quantization effects on the reconstruction of sparse and approximately sparse signals from a reduced set of measurements is analyzed in this paper.
Isidora Stankovic +4 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
FEBS Letters, EarlyView.Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley +1 more source
An Enhanced Photonic-Assisted Sampling Approach for Spectrum-Sparse Signal by Compressed Sensing
IEEE Access, 2022 Spectrum-sparse signals are vital for wideband radar and wireless communication applications. A high-speed analog-to-digital converter (ADC) with the capacities of tens of gigahertz sampling rates is often required to acquire these signals. In this work,
Fangxing Lyu +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
International Journal of Antennas and Propagation, 2016 The partial discharge (PD) detection of electrical equipment is important for the safe operation of power system. The ultrasonic signal generated by the PD in the oil is a broadband signal.
Qing Xie +6 more
doaj +1 more source