Results 51 to 60 of about 72,581 (258)

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant   +11 more
wiley   +1 more source

Sparse regularization method combining SVA for feature enhancement of SAR images

open access: yesElectronics Letters, 2022
Sparse signal processing has been widely used in synthetic aperture radar imaging and feature enhancement of images in the recent decade. Sparse regularization ℓ1 can reduce the imaging noise level and suppress sidelobes.
Zhongqiu Xu   +4 more
doaj   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

A Computerized Bioinspired Methodology for Lightweight and Reliable Neural Telemetry

open access: yesSensors, 2020
Personalized health monitoring of neural signals usually results in a very large dataset, the processing and transmission of which require considerable energy, storage, and processing time. We present bioinspired electroceptive compressive sensing (BeCoS)
Olufemi Adeluyi   +4 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

Accelerated Sparse Microwave Imaging Phase Error Compensation Algorithm Based on Combination of SAR Raw Data Simulator and Map-drift Autofocus Algorithm

open access: yesLeida xuebao, 2016
Sparse microwave imaging is new concept, theory and methodology of microwave imaging, which introduces the sparse signal processing theory to microwave imaging and combines them together to overcome the paradox of increasing system complexity and imaging
Zhang Zhe   +3 more
doaj   +1 more source

Colours of velvet noise

open access: yesElectronics Letters, 2022
Velvet noise is a sparse ternary pseudo‐random signal containing only a small portion of non‐zero values. In this work, the derivation of the spectral properties of velvet noise is presented.
Nils Meyer‐Kahlen   +2 more
doaj   +1 more source

Sparse Image and Signal Processing

open access: yes, 2015
This thoroughly updated new edition presents state of the art sparse and multiscale image and signal processing. It covers linear multiscale geometric transforms, such as wavelet, ridgelet, or curvelet transforms, and non-linear multiscale transforms based on the median and mathematical morphology operators.
Starck, Jean-Luc   +2 more
openaire   +2 more sources

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

open access: yesFEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton   +6 more
wiley   +1 more source

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