Results 41 to 50 of about 4,159 (257)

Multichannel Electromyographic Mapping to Optimize OnabotulinumtoxinA Efficacy in Cervical Dystonia

Tremor and Other Hyperkinetic Movements, 2012
Background: Cervical dystonia (CD) is characterized by sustained, involuntary contraction of head and neck muscles. Botulinum toxin injections are established as safe and effective, but unfortunately 15–25% of patients fail to respond. The aim
Camilla Kilbane, Jill Ostrem, Nicholas Galifianakis, Jamie Grace, Leslie Markun, Graham A. Glass   +5 more
doaj   +1 more source

Evaluation of the quality of life in patients with segmental dystonia [PDF]

, 2012
Background/Aim. Segmental dystonia is an abnormal movement, characterized by involuntary, sustained and repetitive muscular contractions, causing twisting and abnormal posturing of two or more adjacent body parts.
Basurović Nataša, Kostić Vladimir S., Pekmezović Tatjana, Svetel Marina   +3 more
core   +1 more source

Spasmodic Torticollis—A Multicentre Study on Behavioural Aspects II: Signs, Symptoms and Course

Behavioural Neurology, 1996
This paper deals with signs, symptoms and course in spasmodic torticollis (ST). Two hundred and fifty-six patients were included in the study, 59.3% women, 40.7% men. The mean age was 49.1 years.
F. Heinen, C. E. Scheidt, T. Nickel, O. Rayki, J. Wissel, W. Poewe, R. Benecke, G. Arnold, W. Oertel, R. Dengler, G. Deuschl   +10 more
doaj   +1 more source

Service-based survey of dystonia in Munich [PDF]

, 2002
We performed a service-based epidemiological study of dystonia in Munich, Germany. Due to favourable referral and treatment patterns in the Munich area, we could provide confident data from dystonia patients seeking botulinum toxin treatment.
Ben-Shlomo, Y., Ceballos-Baumann, Andres, Conrad, B., Gasser, T., Kamm, C., Konkiewitz, E. C., Trender-Gerhard, I., Warner, T.   +7 more
core   +1 more source

OnabotulinumtoxinA Dosing, Disease Severity, and Treatment Benefit in Patients With Cervical Dystonia: A Cohort Analysis From CD PROBE

Frontiers in Neurology, 2022
IntroductionThe Cervical Dystonia Patient Registry for Observation of OnabotulinumtoxinA Efficacy (CD PROBE) study (ClinicalTrials.gov identifier: NCT00836017), a multicenter, prospective, observational registry, was designed to identify real-world ...
Pinky Agarwal, Pinky Agarwal, Richard Barbano, Henry Moore, Marc Schwartz, Aleksej Zuzek, Marjan Sadeghi, Atul Patel, Atul Patel   +8 more
doaj   +1 more source

Botulinum toxin type A versus botulinum toxin type B for cervical dystonia [PDF]

, 2016
BACKGROUND: This is an update of a Cochrane review first published in 2003. Cervical dystonia is the most common form of focal dystonia and is a disabling disorder characterised by painful involuntary head posturing.
Castelão, M, Costa, J, Duarte, GS, Ferreira, J, Marques, RE, Moore, AP, Rodrigues, FB, Sampaio, C   +7 more
core   +2 more sources

What are the determinants of quality of life in people with cervical dystonia? [PDF]

, 2002
Background: Little is known about the quality of life in patients with cervical dystonia, although pain and depression are relatively common. Objective: To test the hypothesis that an individual’s ability to cope with the disease will modify the ...
Ben-Shlomo, Yoav, Camfield, Laura, Warner, Tom   +2 more
core   +2 more sources

Investigating Sleep Concerns in Cervical Dystonia

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Heterogenous, small cohorts, and co‐occurrence of pain and psychiatric burden complicate understanding of sleep in dystonia. Objective To investigate sleep concerns in cervical dystonia (CD). Methods Longitudinal data from CD‐PROBE on subjects who were toxin‐naïve, new to practice, or without injections for at least 16 weeks were ...
Abhimanyu Mahajan, David Andrés González, Cynthia Comella   +2 more
wiley   +1 more source

Study protocol: multimodal physiotherapy as an add-on treatment to botulinum neurotoxin type A therapy for patients with cervical dystonia: DysPT-multi—a prospective, multicentre, single-blind, randomized, controlled study

Trials, 2021
Background Botulinum neurotoxin (BoNT) is currently the best therapeutic option in the treatment for cervical dystonia (CD). Additional treatments like physiotherapy (PT) may even improve the results of the BoNT injection with type A (BoNT-A), but there ...
Christian Werner, Dana Loudovici-Krug, Steffen Derlien, Florian Rakers, Ulrich C. Smolenski, Thomas Lehmann, Norman Best, Albrecht Günther   +7 more
doaj   +1 more source

Dystonia Scales for Children: Challenges and Obstacles in DBS Practice

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Dystonia in pediatric patients often coexists with other movement disorders and neurodevelopmental issues. Current rating scales for evaluating pediatric deep brain stimulation (DBS) candidates are not universally applicable and often require a non‐validated combination of the existing scales.
Marcela Montiel, Carolina Gorodetsky, Laura Cif, Nardo Nardocci, Alfonso Fasano   +4 more
wiley   +1 more source