Results 1 to 10 of about 59,662 (243)
Pediatric Neurology Briefs, 1988 Four infants with partial seizures evolving to infantile spasms were investigated using simultaneous EEG-video-telemetry recording in the Dept of Pediatrics, Nagoya University, Nagoya, and Division of Pediatric Neurology, Central Hospital, Aichi ...
J Gordon Millichap
doaj +7 more sources
Genetic Classification of Infantile Spasms
Pediatric Neurology Briefs, 2012 Researchers from University of Washington, Seattle, WA, and Washington University, St Louis, MO propose a genetic and biologic classification of infantile spasms. Infantile spasms are of 2 main groups: those with known or unknown predisposing genotypes.
J Gordon Millichap
doaj +2 more sources
Current trends in the treatment of infantile spasms
Neuropsychiatric Disease and Treatment, 2009 Chang-Yong TsaoClinical Pediatrics and Neurology, The Ohio State University, College of Medicine, Columbus, Ohio, USAAbstract: Infantile spasms are an epilepsy syndrome with distinctive features, including age onset during infancy, characteristic ...
Chang-Yong Tsao
doaj +1 more source
Infantile Spasms Respond Poorly to Topiramate
Pediatric Neurology, 2015 Introduction: Infantile spasms are seizures typical of an age-related epileptic encephalopathy. Although evidence supporting topiramate for infantile spasms is lacking, many clinicians use it for this indication.
Amanda Weber +2 more
exaly +2 more sources
Long-term developmental outcome in infantile epileptic spasms syndrome after high-dose prednisolone and vigabatrin treatment. [PDF]
Epilepsia OpenAbstract Objective To evaluate long‐term developmental outcomes and identify independent predictors of favorable developmental outcomes at 3 years of age in children with infantile epileptic spasms syndrome (IESS) treated with a standardized stepwise vigabatrin and high‐dose prednisolone protocol.
Jang S +5 more
europepmc +2 more sources
Treatment of Symptomatic Infantile Spasms
Pediatric Neurology Briefs, 2013 Investigators at Tokyo Women's Medical University studied the clinical, radiological, and EEG characteristics of 69 patients with infantile spasms (IS) followed for 3-74 months (mean 18 months) after initial cessation of epileptic spasms (ES).
J Gordon Millichap
doaj +2 more sources
Impact of vigabatrin on risk of relapse of infantile spasms. [PDF]
Epilepsia OpenAbstract Objective Vigabatrin is an effective treatment for infantile epileptic spasms syndrome (IESS), but relapse remains a clinical challenge. The ideal dose and duration of treatment after response are unknown. We set out to identify treatment‐related predictors of IESS relapse after initial vigabatrin response. Methods We conducted a retrospective
Carmenate YI +5 more
europepmc +2 more sources
Pathophysiology of Infantile Spasms [PDF]
Pediatric Neurology Briefs, 1993 An age-specific endogenous-convulsant hypothesis implicating corticotropin-releasing hormone (CRH), an excitant neuropeptide suppressed by ACTH/steroids, is proposed for the pathophysiology of massive infantile spasms in a report from the University of ...
J Gordon Millichap
doaj +2 more sources
Management of Infantile Epileptic Spasms Syndrome: A survey of US pediatric hospitals. [PDF]
Epilepsia OpenAbstract Objective To evaluate the management practices of Infantile Epileptic Spasms Syndrome (IESS) across tertiary pediatric hospitals in the United States using a survey‐based approach. Methods A 21‐question survey focused on management setting, work‐up, follow‐up and treatment was created and sent to 45 member institutions of the Pediatric ...
Katyayan A +16 more
europepmc +2 more sources
Pediatric Neurology Briefs, 1995 Behavioral and EEG asymmetry and asynchrony of 8,680 infantile spasms were analysed in a review of 75 consecutive video-EEG recordings performed at UCLA Medical Center, Los Angeles from 1982 to 1992.
J Gordon Millichap
doaj +2 more sources