Results 1 to 10 of about 142,627 (190)

Seizure Prediction Analysis of Infantile Spasms

open access: yesIEEE Transactions on Neural Systems and Rehabilitation Engineering, 2023
Infantile spasms (IS) is a typical childhood epileptic disorder with generalized seizures. The sudden, frequent and complex characteristics of infantile spasms are the main causes of sudden death, severe comorbidities and other adverse consequences ...
Runze Zheng   +5 more
doaj   +2 more sources

Clinical profile and treatment of infantile spasms using vigabatrin and ACTH - a developing country perspective [PDF]

open access: yesBMC Pediatrics, 2010
Background Infantile spasms represent a serious epileptic syndrome that occurs in the early infantile age. ACTH and Vigabatrin are actively investigated drugs in its treatment.
Ishaque Sidra   +3 more
doaj   +5 more sources

Clinical profile of vigabatrin as monotherapy for treatment of infantile spasms [PDF]

open access: yesNeuropsychiatric Disease and Treatment, 2010
Jason T Lerner1, Noriko Salamon2, Raman Sankar1,31Departments of Pediatrics, 2Radiological Sciences, 3Neurology, David Geffen School of Medicine, University of California Los Angeles and Mattel Children’s Hospital at UCLA, Los Angeles, CA ...
Jason T Lerner   +2 more
doaj   +5 more sources

Current trends in the treatment of infantile spasms [PDF]

open access: yesNeuropsychiatric Disease and Treatment, 2009
Chang-Yong TsaoClinical Pediatrics and Neurology, The Ohio State University, College of Medicine, Columbus, Ohio, USAAbstract: Infantile spasms are an epilepsy syndrome with distinctive features, including age onset during infancy, characteristic ...
Chang-Yong Tsao
doaj   +3 more sources

Neurotransmission Sex Dichotomy in the Rat Hypothalamic Paraventricular Nucleus in Healthy and Infantile Spasm Model [PDF]

open access: yesCurrent Issues in Molecular Biology
We profiled the gene expressions in the hypothalamic paraventricular nuclei of 12 male and 12 female pups from a standard rat model of infantile spasms to determine the sex dichotomy of the neurotransmission genomic fabrics.
Dumitru Andrei Iacobas   +6 more
doaj   +2 more sources

Infantile Spasms in Pediatric Down Syndrome: Potential Mechanisms Driving Therapeutic Considerations [PDF]

open access: yesChildren
Infantile spasms are common in Down Syndrome (DS), but the mechanisms by which DS predisposes to this devastating epilepsy syndrome are unclear.
Carl E. Stafstrom, Li-Rong Shao
doaj   +2 more sources

Landscape of genetic infantile epileptic spasms syndrome—A multicenter cohort of 124 children from India

open access: yesEpilepsia Open, 2023
Literature on the genotypic spectrum of Infantile Epileptic Spasms Syndrome (IESS) in children is scarce in developing countries. This multicentre collaboration evaluated the genotypic and phenotypic landscape of genetic IESS in Indian children.
Balamurugan Nagarajan   +23 more
semanticscholar   +1 more source

Mechanisms of infantile epileptic spasms syndrome: What have we learned from animal models?

open access: yesEpilepsia, 2023
The devastating developmental and epileptic encephalopathy of infantile epileptic spasms syndrome (IESS) has numerous causes, including, but not limited to, brain injury, metabolic, and genetic conditions.
Andy Cheuk-Him Ng   +4 more
semanticscholar   +1 more source

De novo variants in MAST4 related to neurodevelopmental disorders with developmental delay and infantile spasms: Genotype-phenotype association

open access: yesFrontiers in Molecular Neuroscience, 2023
Objective This study aims to prove that the de novo variants in MAST4 gene are associated with neurodevelopmental disorders (NDD) with developmental delay (DD) and infantile spasm (IS) and to determine the genotype-phenotype correlations.
Xi Zhang   +11 more
semanticscholar   +1 more source

Fifteen years of real‐world data on the use of vigabatrin in individuals with infantile epileptic spasms syndrome

open access: yesEpilepsia, 2023
This study was undertaken to evaluate our treatment algorithm for infantile epileptic spasms syndrome (IESS) used between 2000 and 2018.
M. Kuchenbuch   +4 more
semanticscholar   +1 more source

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