Results 1 to 10 of about 8,604 (120)
Brain Magnetic Resonance Imaging Findings in Infantile Spasms
Neurology International, 2022 Background: Infantile spasms are an age-specific epileptic disorder. They occur in infancy and early childhood. They can be caused by multiple etiologies. Structural abnormalities represent an important cause of infantile spasms. Brain magnetic resonance
Osama Y. Muthaffar
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Seizure Prediction Analysis of Infantile Spasms
IEEE Transactions on Neural Systems and Rehabilitation Engineering, 2023 Infantile spasms (IS) is a typical childhood epileptic disorder with generalized seizures. The sudden, frequent and complex characteristics of infantile spasms are the main causes of sudden death, severe comorbidities and other adverse consequences ...
Runze Zheng +5 more
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A pulse rapamycin therapy for infantile spasms and associated cognitive decline
Neurobiology of Disease, 2011 Infantile spasms are seizures manifesting within a spectrum of epileptic encephalopathies of infancy that often lead to cognitive impairment. Their current therapies, including adrenocorticotropic hormone (ACTH), high dose steroids, or vigabatrin, are ...
Emmanuel Raffo +4 more
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Genetic Classification of Infantile Spasms
Pediatric Neurology Briefs, 2012 Researchers from University of Washington, Seattle, WA, and Washington University, St Louis, MO propose a genetic and biologic classification of infantile spasms. Infantile spasms are of 2 main groups: those with known or unknown predisposing genotypes.
J Gordon Millichap
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Aicardi Syndrome: A Rare Cause of Infantile Spasms [PDF]
International Journal of Anatomy Radiology and SurgeryInfantile spasms may occur in isolation or as part of multiple neurodevelopmental syndromes. We report an eight-month-old female infant presenting with infantile spasms, developmental delay, and characteristic features of Aicardi syndrome ...
Rituparna Das +2 more
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UK Infantile Spasms Study: Effect of Time to Treatment and Age at Onset on Developmental Outcome
Pediatric Neurology Briefs, 2011 The effects of lead time to treatment (time from onset of spasms to start of treatment), age at onset of spasms, etiology, and treatment on developmental outcome at 4 years were investigated using multiple linear regression in 77 infants with spasms ...
J Gordon Millichap
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Safety and Efficacy of Vigabatrin for the Treatment of Infantile Spasms
Journal of Central Nervous System Disease, 2011 In 2009, vigabatrin became the first FDA approved medication for the treatment of infantile spasms in the United States. There are few well-designed prospective studies comparing the drug to placebo or other modalities used in the treatment of infantile ...
Michele A. Faulkner, Justin A. Tolman
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Treatment of Symptomatic Infantile Spasms
Pediatric Neurology Briefs, 2013 Investigators at Tokyo Women's Medical University studied the clinical, radiological, and EEG characteristics of 69 patients with infantile spasms (IS) followed for 3-74 months (mean 18 months) after initial cessation of epileptic spasms (ES).
J Gordon Millichap
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Neurobiology of Disease, 2015 Abnormal high frequency oscillations (HFOs) in EEG recordings are thought to be reflections of mechanisms responsible for focal seizure generation in the temporal lobe and neocortex. HFOs have also been recorded in patients and animal models of infantile
James D. Frost, Jr. +5 more
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Pediatric Neurology Briefs, 2001 Early electroclinical manifestations and treatment responses were evaluated by video-EEG in 44 infants with infantile spasms.
J Gordon Millichap
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