Results 1 to 10 of about 205,326 (333)

Long-term developmental outcome in infantile epileptic spasms syndrome after high-dose prednisolone and vigabatrin treatment. [PDF]

Epilepsia Open
Abstract Objective To evaluate long‐term developmental outcomes and identify independent predictors of favorable developmental outcomes at 3 years of age in children with infantile epileptic spasms syndrome (IESS) treated with a standardized stepwise vigabatrin and high‐dose prednisolone protocol.
Jang S, Shin HJ, Kim SH, Lee JS, Ko A, Kang HC.   +5 more
europepmc   +4 more sources

Seizure Prediction Analysis of Infantile Spasms

IEEE Transactions on Neural Systems and Rehabilitation Engineering, 2023
Infantile spasms (IS) is a typical childhood epileptic disorder with generalized seizures. The sudden, frequent and complex characteristics of infantile spasms are the main causes of sudden death, severe comorbidities and other adverse consequences ...
Runze Zheng, Jiuwen Cao, Yuanmeng Feng, Xiaodan Zhao, Tiejia Jiang, Feng Gao   +5 more
doaj   +2 more sources

Impact of vigabatrin on risk of relapse of infantile spasms. [PDF]

Epilepsia Open
Abstract Objective Vigabatrin is an effective treatment for infantile epileptic spasms syndrome (IESS), but relapse remains a clinical challenge. The ideal dose and duration of treatment after response are unknown. We set out to identify treatment‐related predictors of IESS relapse after initial vigabatrin response. Methods We conducted a retrospective
Carmenate YI, Ahn HE, Peters HR, Nariai H, Rajaraman RR, Hussain SA.   +5 more
europepmc   +3 more sources

Time-frequency characteristics of scalp high-frequency oscillations provide complementary biomarkers in infantile epileptic spasms syndrome. [PDF]

Exp Physiol
Abstract Infantile epileptic spasms syndrome (IESS) is characterized by epileptic spasms (ES) in infants and hypsarrhythmia on EEG. High‐frequency oscillations (HFOs), defined as oscillatory events at >80 Hz, reflect rapid spatiotemporal dynamics of cortical activity and might serve as novel biomarkers for epilepsy.
Yamaguchi S, Maeda K, Ishihara N, Furukawa G, Tsuboi H, Osakabe K, Sugimoto K, Ichino N.   +7 more
europepmc   +3 more sources

Seizure modulation by the gut microbiota and tryptophan-kynurenine metabolism in an animal model of infantile spasms

EBioMedicine, 2022
Summary Background The infantile spasms syndrome is an early-onset epileptic encephalopathy presenting in the first 2 years of life, often with severe developmental consequences.
Morris H Scantlebury, Chunlong Mu, Jong M Rho   +2 more
exaly   +2 more sources

Management of Infantile Epileptic Spasms Syndrome: A survey of US pediatric hospitals. [PDF]

Epilepsia Open
Abstract Objective To evaluate the management practices of Infantile Epileptic Spasms Syndrome (IESS) across tertiary pediatric hospitals in the United States using a survey‐based approach. Methods A 21‐question survey focused on management setting, work‐up, follow‐up and treatment was created and sent to 45 member institutions of the Pediatric ...
Katyayan A, Briscoe C, Bhalla S, Bhatia S, Erdemir G, Harini C, Hunter SE, Mytinger JR, Nie D, Pasupuleti A, Patel SH, Samanta D, Karamian AS, Singh A, Sirsi D, Takacs DS, Hussain SA.   +16 more
europepmc   +4 more sources

Infantile Epileptic Spasms Syndrome Complicating Mosaic Down-Turner Syndrome: A Case Report. [PDF]

Clin Case Rep
Shahrori M, Nofal K, Alkhawaja HH, Mohsen W, Alzamari AA.   +4 more
europepmc   +3 more sources

Hemimegalencephaly With Diffuse Cortical Malformation in a Child With Drug-Resistant Infantile Epileptic Spasms: A Case Report. [PDF]

Cureus
Essaher B, Sqalli Houssaini Y, Amar S, En Nouali H, Boui M.   +4 more
europepmc   +3 more sources

<i>RFX3</i> Pathogenic Variants as a Rare Cause of Infantile Epileptic Spasms Syndrome. [PDF]

Int J Mol Sci
Ceraolo G, Spoto G, Trivisano M, Federico C, Vinci M, Calì F, Treccarichi S, Musumeci A, Di Rosa G, Specchio N, Nicotera AG.   +10 more
europepmc   +2 more sources

Health-Related Quality of Life and Family Impact in Young Children with Infantile Epileptic Spasms Syndrome: A Cross-Sectional Caregiver-Reported Study [PDF]

J Clin Med
Natalia Kasaraba, Anna Rozensztrauch
europepmc   +2 more sources