Results 1 to 10 of about 133,799 (192)

Seizure Prediction Analysis of Infantile Spasms

open access: yesIEEE Transactions on Neural Systems and Rehabilitation Engineering, 2023
Infantile spasms (IS) is a typical childhood epileptic disorder with generalized seizures. The sudden, frequent and complex characteristics of infantile spasms are the main causes of sudden death, severe comorbidities and other adverse consequences ...
Runze Zheng   +5 more
doaj   +2 more sources

Neurotransmission Sex Dichotomy in the Rat Hypothalamic Paraventricular Nucleus in Healthy and Infantile Spasm Model [PDF]

open access: yesCurrent Issues in Molecular Biology
We profiled the gene expressions in the hypothalamic paraventricular nuclei of 12 male and 12 female pups from a standard rat model of infantile spasms to determine the sex dichotomy of the neurotransmission genomic fabrics.
Dumitru Andrei Iacobas   +6 more
doaj   +2 more sources

Infantile Spasms in Children With Down Syndrome: Identification and Treatment Response

open access: yesGlobal Pediatric Health, 2019
Objectives. To evaluate infantile spasms in children with Down syndrome including assessment of efficacy of treatments, presence of treatment lag, and to identify risk factors that may predict the occurrence of infantile spasms in this population ...
Dee Daniels CPNP, RN, MSN   +5 more
doaj   +2 more sources

Infantile Spasms in Pediatric Down Syndrome: Potential Mechanisms Driving Therapeutic Considerations [PDF]

open access: yesChildren
Infantile spasms are common in Down Syndrome (DS), but the mechanisms by which DS predisposes to this devastating epilepsy syndrome are unclear.
Carl E. Stafstrom, Li-Rong Shao
doaj   +2 more sources

Landscape of genetic infantile epileptic spasms syndrome—A multicenter cohort of 124 children from India

open access: yesEpilepsia Open, 2023
Literature on the genotypic spectrum of Infantile Epileptic Spasms Syndrome (IESS) in children is scarce in developing countries. This multicentre collaboration evaluated the genotypic and phenotypic landscape of genetic IESS in Indian children.
Balamurugan Nagarajan   +23 more
semanticscholar   +1 more source

Mechanisms of infantile epileptic spasms syndrome: What have we learned from animal models?

open access: yesEpilepsia, 2023
The devastating developmental and epileptic encephalopathy of infantile epileptic spasms syndrome (IESS) has numerous causes, including, but not limited to, brain injury, metabolic, and genetic conditions.
Andy Cheuk-Him Ng   +4 more
semanticscholar   +1 more source

De novo variants in MAST4 related to neurodevelopmental disorders with developmental delay and infantile spasms: Genotype-phenotype association

open access: yesFrontiers in Molecular Neuroscience, 2023
Objective This study aims to prove that the de novo variants in MAST4 gene are associated with neurodevelopmental disorders (NDD) with developmental delay (DD) and infantile spasm (IS) and to determine the genotype-phenotype correlations.
Xi Zhang   +11 more
semanticscholar   +1 more source

EEG‐based spatiotemporal dynamics of fast ripple networks and hubs in infantile epileptic spasms

open access: yesEpilepsia Open, 2023
Infantile epileptic spasms (IS) are epileptic seizures that are associated with increased risk for developmental impairments, adult epilepsies, and mortality.
Ioana Ma Samfira   +5 more
semanticscholar   +1 more source

Fifteen years of real‐world data on the use of vigabatrin in individuals with infantile epileptic spasms syndrome

open access: yesEpilepsia, 2023
This study was undertaken to evaluate our treatment algorithm for infantile epileptic spasms syndrome (IESS) used between 2000 and 2018.
M. Kuchenbuch   +4 more
semanticscholar   +1 more source

Etiologic Classification of 541 Infantile Spasms Cases: A Cohort Study

open access: yesFrontiers in Pediatrics, 2022
Objective To explore the etiology of infantile spasms (IS) in a large Chinese cohort based on the United States National Infantile Spasms Consortium (NISC) classification.
P. Peng   +9 more
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy