Results 121 to 130 of about 132,025 (234)

What defines response to vagus nerve stimulation in children with drug‐resistant epilepsy? A prospective cohort study from the CONNECTiVOS collaboration

Epilepsia, EarlyView.
Abstract Objectives Responsiveness to vagus nerve stimulation (VNS) in children with drug‐resistant epilepsy (DRE) is often defined based on reduction in seizure frequency, typically at the 50% threshold, with limited consideration to the effects of therapy on seizure severity and health‐related quality of life (HRQoL). In the current report, we sought
Farbod Niazi, Karim Mithani, Hrishikesh Suresh, Simeon M. Wong, Ivanna Yau, Lyndsey McRae, Thiemo F. Dinger, James T. Rutka, Ayako Ochi, Hiroshi Otsubo, Shelly Weiss, Lauren Sham, Elizabeth Donner, Vann Chau, Aristides Hadjinicolaou, Philippe Major, Alexander G. Weil, Jignesh Tailor, Taylor J. Abel, Madison Remick, Emefa Akwayena, Dewi Schrader, Robert J. Bollo, Matthew D. Smyth, Diana Aum, Sean Lew, Shelly Wang, Toba Niazi, Jeffrey S. Raskin, Elysa Widjaja, Howard L. Weiner, Nisha Gadgil, Melissa A. LoPresti, Gregory W. Albert, Aria Fallah, Elizabeth Kerr, Mary Lou Smith, Puneet Jain, George M. Ibrahim   +38 more
wiley   +1 more source

Clinical profile of vigabatrin as monotherapy for treatment of infantile spasms

Neuropsychiatric Disease and Treatment, 2010
Jason T Lerner1, Noriko Salamon2, Raman Sankar1,31Departments of Pediatrics, 2Radiological Sciences, 3Neurology, David Geffen School of Medicine, University of California Los Angeles and Mattel Children’s Hospital at UCLA, Los Angeles, CA ...
Jason T Lerner, Noriko Salamon, Raman Sankar   +2 more
doaj  

Vigabatrin for Infantile Spasms

Pediatric Neurology Briefs, 1999
The efficacy of vigabatrin (VGB) as the first, and adrenocorticotropin hormone (ACTH) or valproate (VPA) as the second, treatment of choice for newly diagnosed infantile spasms was evaluated in 42 infants treated at the University of Helsinki, Finland.
openaire   +3 more sources

Examining the association between placental malperfusion assessed by histopathological examination and child and adolescent neurodevelopment: a systematic review

Journal of Child Psychology and Psychiatry, EarlyView.
Background Placental malperfusion, categorised into maternal vascular malperfusion (MVM) and foetal vascular malperfusion (FVM), is a main placental pathology known to affect placental functioning and offspring outcomes. The aim of this review is to evaluate the association between exposure to placental malperfusion and offspring neurodevelopment from ...
Noha Ibrahim, Sydni A. Weissgold, Lucy Brink, Ibtihal Mahgoub, Ben Carter, Vaheshta Sethna, Hein Odendaal   +6 more
wiley   +1 more source

Characterizing Diagnostic Delays in Metachromatic Leukodystrophy: A Real‐World Data Approach

Journal of Inherited Metabolic Disease, Volume 48, Issue 4, July 2025.
ABSTRACT Neurodegeneration in metachromatic leukodystrophy (MLD) may be preceded by systemic complications. Characterization of these features is critical to define barriers to early diagnosis and treatment eligibility for gene therapy. We utilized medical billing (claims) datasets and a natural history study to capture pre‐diagnosis MLD‐related events.
Ali Mohajer, Anjana Sevagamoorthy, Karen Bean, Sylvia Mutua, Francis Pang, Laura Ann Adang   +5 more
wiley   +1 more source

Risk of autism spectrum disorder in children with infantile epileptic spasms syndrome: a retrospective study in a single center in Brazil

Jornal de Pediatria
Objective: This study aimed to investigate the prevalence of autism spectrum disorder and its possible correlations with clinical characteristics in patients with infantile epileptic spasms syndrome in a single center in Brazil.
Marília Barbosa de Matos, Paulo Breno Noronha Liberalesso, Tiago dos Santos Bara, Paula Carolina Martins Alves Gomes, Bianca Simone Zeigelboim, Jair Mendes Marques, Mara L. Cordeiro   +6 more
doaj  

Prediction of cerebral palsy and cognitive delay among high‐risk children in a developing nation: A successful early detection programme

Developmental Medicine &Child Neurology, Volume 67, Issue 7, Page 892-900, July 2025.
201 infants at risk for developmental disorders were assessed using two General Movements Assessments (GMA) and one Hammersmith Infant Neurological Examination (HINE), integrated into routine follow up care. Developmental outcome was assessed with a neurologic examination at 2 years, and the Bayley Scales of Infant and Toddler Development at 2 ‐ 3.5 ...
Gemunu Hewawitharana, Nuwan Darshana ILA, Asha Madhushani UI, Sadeepi Chathuranga DP, Nirosha Priyangika DI, Bimba Hewawitharana, Champa Wijesinghe, Piyadasa Kodituwakku, John Phillips, RG Yashoda Madumadhavie, RD Susantha Kumara, DJ Danunga Mihiran, KV. Kanchana Nilukshika   +12 more
wiley   +1 more source

Salvage Trans‐Sylvian Peri‐Insular Hemispherotomy After Embolic Hemispherectomy

Annals of the Child Neurology Society, Volume 3, Issue 2, Page 110-114, June 2025.
ABSTRACT Background Hemispherectomy and hemispherotomy represent well‐established treatments for drug‐resistant hemispheric epilepsy. An alternative endovascular procedure has been explored for cases with challenging surgical anatomy, which seeks to achieve the clinical effect of hemispherectomy via embolization of the major cerebral arteries and ...
Michael E. Baumgartner, Sudha Kessler, Kathleen Galligan, James E. Baumgartner, Benjamin C. Kennedy   +4 more
wiley   +1 more source

Expert opinions on pediatric EEG training for non‐epilepsy specialists in sub‐Saharan Africa

Epileptic Disorders, Volume 27, Issue 3, Page 374-388, June 2025.
Abstract Ideally, pediatric electroencephalograms (EEGs) should be performed by accredited neurophysiology technologists and interpreted by specialists trained in epileptology However, low‐ and middle‐income countries (LMICs) lack such specialists.
Veena Kander, Kette D. Valente, Jaime Carrizosa, Jorge Vidaurre, Archana A. Patel, Chahnez Charfi Triki, Ghaieb Aljandeel, Gagandeep Singh, Mitsuhiro Kato, Lala Seck, Zeinab Kone, Sándor Beniczky, Melody T. Asukile, Gretchen L. Birbeck, Kevin Jones, Geraldine Boylan, Joanne Hardman, Jo M. Wilmshurst   +17 more
wiley   +1 more source

Exploring biomarkers of neurodegeneration in epilepsy: Critical insights

Epileptic Disorders, Volume 27, Issue 3, Page 341-357, June 2025.
Abstract The advent of biofluid biomarkers for neurodegenerative disorders has precipitated a surge in recent evidence regarding their role in epilepsy. In this literature review, we examine the diagnostic, prognostic, and therapeutic potential of several biomarkers, including amyloid‐beta (Aβ) protein, total (t‐tau), phosphorylated tau (p‐tau) protein,
Rida Farhan, Syeda Amrah Hashmi, Jaideep Kapur, Anelyssa D'Abreu, Vineet Punia, Carol Manning, Vanessa L. Smith, Ifrah Zawar   +7 more
wiley   +1 more source