Results 21 to 30 of about 132,025 (234)
EEG biomarkers for the diagnosis and treatment of infantile spasms
Frontiers in Neurology, 2022 Early diagnosis and treatment are critical for young children with infantile spasms (IS), as this maximizes the possibility of the best possible child-specific outcome.
Blanca Romero Milà +4 more
semanticscholar +1 more source
Inequities in Therapy for Infantile Spasms: A Call to Action
Annals of Neurology, 2022 The aim of this study was to determine whether selection of treatment for children with infantile spasms (IS) varies by race/ethnicity.
Fiona M. Baumer +22 more
semanticscholar +1 more source
Brain Magnetic Resonance Imaging Findings in Infantile Spasms
Neurology International, 2022 Background: Infantile spasms are an age-specific epileptic disorder. They occur in infancy and early childhood. They can be caused by multiple etiologies. Structural abnormalities represent an important cause of infantile spasms. Brain magnetic resonance
Osama Y. Muthaffar
doaj +1 more source
Neurology, 2022 Background and Objectives Standard therapies (adrenocorticotropic hormone [ACTH], oral steroids, or vigabatrin) fail to control infantile spasms in almost half of children. Early identification of nonresponders could enable rapid initiation of sequential
Christopher J. Yuskaitis +14 more
semanticscholar +1 more source
Response to sequential treatment with prednisolone and vigabatrin in infantile spasms
Journal of Paediatrics and Child Health, 2022 To report response to first treatment in infants with infantile spasms (IS), including incremental benefit of prednisolone 60 mg/day and vigabatrin following prednisolone 40 mg/day failure in infants commenced on the United Kingdom Infantile Spasms Study
Winston Dzau +6 more
semanticscholar +1 more source
Epilepsia Open, EarlyView., 2022 Abstract Epilepsy syndromes during the early years of life may be attributed to an acquired insult, such as hypoxic–ischemic injury, infection, status epilepticus, or brain trauma. These conditions are frequently modeled in experimental rodents to delineate mechanisms of epileptogenesis and investigate novel therapeutic strategies.
Anna‐Maria Katsarou +7 more
wiley +1 more source
Tuber Locations Associated with Infantile Spasms Map to a Common Brain Network
Annals of Neurology, 2021 Approximately 50% of patients with tuberous sclerosis complex develop infantile spasms, a sudden onset epilepsy syndrome associated with poor neurological outcomes.
A. Cohen +16 more
semanticscholar +1 more source
Brain Communications, 2021 Infantile spasms (IS) syndrome is a catastrophic, epileptic encephalopathy of infancy that is often refractory to current antiepileptic therapies. The ketogenic diet (KD) has emerged as an alternative treatment for patients with medically intractable ...
Anamika Choudhary +8 more
semanticscholar +1 more source
Brazilian experts' consensus on the treatment of infantile epileptic spasm syndrome in infants
Arquivos de Neuro-Psiquiatria, 2023 Background Infantile epileptic spasms syndrome (IESS) is a rare but severe condition affecting children early and is usually secondary to an identifiable brain disorder.
Letícia Pereira de Brito Sampaio +7 more
doaj +1 more source
Comparative Effectiveness of Initial Treatment for Infantile Spasms in a Contemporary US Cohort
Neurology, 2021 Objective To compare the effectiveness of initial treatment for infantile spasms. Methods The National Infantile Spasms Consortium prospectively followed up children with new-onset infantile spasms that began at age 2 to 24 months at 23 US centers (2012 ...
Z. Grinspan +20 more
semanticscholar +1 more source